日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The FAM13A Long Isoform Regulates Cilia Movement and Coordination in Airway Mucociliary Transport

FAM13A 长同工酶调节气道粘膜纤毛运输中的纤毛运动和协调

Ashleigh Howes, Clare Rogerson, Nikolai Belyaev, Tina Karagyozova, Radu Rapiteanu, Ricardo Fradique, Nicola Pellicciotta, David Mayhew, Catherine Hurd, Stefania Crotta, Tanya Singh, Kevin Dingwell, Anniek Myatt, Navot Arad, Hikmatyar Hasan, Hielke Bijlsma, Aliza Panjwani, Vinaya Vijayan, George Youn

CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation

CARD14 信号体的形成与其内体移位和 mTORC1 诱导的角质形成细胞增殖有关

Paul A O'Sullivan, Aigerim Aidarova, Inna S Afonina, Joan Manils, Teresa L M Thurston, Rachael Instrell, Michael Howell, Stefan Boeing, Sashini Ranawana, Melanie B Herpels, Riwia Chetian, Matilda Bassa, Helen Flynn, David Frith, Ambrosius P Snijders, Ashleigh Howes, Rudi Beyaert, Anne M Bowcock, Ste

CARD14E138A signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

角质形成细胞中的CARD14E138A信号通路诱导TNF依赖性皮肤和全身炎症

Joan Manils # ,Louise V Webb # ,Ashleigh Howes ,Julia Janzen ,Stefan Boeing ,Anne M Bowcock ,Steven C Ley

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation

银屑病突变破坏 CARD14 自身抑制,促进 BCL10-MALT1 依赖性 NF-κB 激活

Ashleigh Howes, Paul A O'Sullivan, Felix Breyer, Ashavari Ghose, Li Cao, Daniel Krappmann, Anne M Bowcock, Steven C Ley

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

型干扰素的差异产生决定了 C57BL/6 和 BALB/c 巨噬细胞产生的 IL-10 和促炎细胞因子的相互水平

Ashleigh Howes, Christina Taubert, Simon Blankley, Natasha Spink, Xuemei Wu, Christine M Graham, Jiawen Zhao, Margarida Saraiva, Paola Ricciardi-Castagnoli, Gregory J Bancroft, Anne O'Garra

Type I IFN induces IL-10 production in an IL-27-independent manner and blocks responsiveness to IFN-γ for production of IL-12 and bacterial killing in Mycobacterium tuberculosis-infected macrophages

型干扰素以 IL-27 非依赖的方式诱导 IL-10 的产生,并阻断结核分枝杆菌感染的巨噬细胞对 IFN-γ 产生 IL-12 和杀死细菌的反应

Finlay W McNab, John Ewbank, Ashleigh Howes, Lucia Moreira-Teixeira, Anna Martirosyan, Nico Ghilardi, Margarida Saraiva, Anne O'Garra