日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux

自噬减少Occludin的降解并促进其膜定位,从而增强肠道上皮紧密连接屏障抵御旁细胞大分子通量

Kushal Saha, Ashwinkumar Subramenium Ganapathy, Alexandra Wang, Nathan Michael Morris, Eric Suchanec, Wei Ding, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot

Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation

α-生育酚醌介导的芳烃受体激活调节炎症诱导细胞因子的产生并减轻肠道炎症

Kushal Saha ,Ashwinkumar Subramenium Ganapathy ,Alexandra Wang ,Priya Arumugam ,Nathan Michael Morris ,Leonard Harris ,Gregory Yochum ,Walter Koltun ,Gary H Perdew ,Meghali Nighot ,Thomas Ma ,Prashant Nighot

Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways

α-生育酚醌通过AhR和Nrf2通路差异性地调节claudin蛋白,从而增强肠上皮紧密连接屏障。

Ashwinkumar Subramenium Ganapathy ,Kushal Saha ,Alexandra Wang ,Priya Arumugam ,Viszwapriya Dharmaprakash ,Gregory Yochum ,Walter Koltun ,Meghali Nighot ,Gary Perdew ,Todd A Thompson ,Thomas Ma ,Prashant Nighot

AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability

AP2M1 通过内吞作用和与 LC3 的相互作用介导自噬诱导的 CLDN2(claudin 2)降解,并降低肠上皮紧密连接通透性

Ashwinkumar Subramenium Ganapathy, Kushal Saha, Eric Suchanec, Vikash Singh, Aayush Verma, Gregory Yochum, Walter Koltun, Meghali Nighot, Thomas Ma, Prashant Nighot

Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis

基质金属蛋白酶 MMP-12 促进巨噬细胞跨越肠上皮紧密连接迁移,并加重实验性结肠炎的严重程度。

Meghali Nighot,Ashwinkumar Subramenium Ganapathy,Kushal Saha,Eric Suchanec,Eliseo F Castillo,Alyssa Gregory,Steven Shapiro,Thomas Ma,Prashant Nighot

Proteomic and Systematic Functional Profiling Unveils Citral Targeting Antibiotic Resistance, Antioxidant Defense, and Biofilm-Associated Two-Component Systems of Acinetobacter baumannii To Encumber Biofilm and Virulence Traits

蛋白质组学和系统功能分析揭示柠檬醛靶向鲍曼不动杆菌的抗生素耐药性、抗氧化防御和生物膜相关双组分系统,以阻碍生物膜和毒力特性

Anthonymuthu Selvaraj, Alaguvel Valliammai, Pandiyan Muthuramalingam, Sivasamy Sethupathy, Ganapathy Ashwinkumar Subramenium, Manikandan Ramesh, Shunmugiah Karutha Pandian

Intestinal epithelial tight junction barrier regulation by autophagy-related protein ATG6/beclin 1

自噬相关蛋白ATG6/beclin 1对肠上皮紧密连接屏障的调节

Morgan Wong, Ashwinkumar Subramenium Ganapathy, Eric Suchanec, Laura Laidler, Thomas Ma, Prashant Nighot

Umbelliferone Impedes Biofilm Formation and Virulence of Methicillin-Resistant Staphylococcus epidermidis via Impairment of Initial Attachment and Intercellular Adhesion

伞形酮通过损害初始附着和细胞间粘附来阻碍生物膜形成和耐甲氧西林表皮葡萄球菌的毒力

Thirukannamangai Krishnan Swetha, Murugesan Pooranachithra, Ganapathy Ashwinkumar Subramenium, Velayutham Divya, Krishnaswamy Balamurugan, Shunmugiah Karutha Pandian

covR Mediated Antibiofilm Activity of 3-Furancarboxaldehyde Increases the Virulence of Group A Streptococcus

covR介导的3-呋喃甲醛抗生物膜活性增强A群链球菌的毒力

Ashwinkumar Subramenium, Ganapathy; Viszwapriya, Dharmaprakash; Iyer, Prasanth Mani; Balamurugan, Krishnaswamy; Karutha Pandian, Shunmugiah