日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Adeno-associated virus gene replacement for recessive inner ear dysfunction: Progress and challenges

腺相关病毒基因替代疗法治疗隐性内耳功能障碍:进展与挑战

Askew, Charles; Chien, Wade W

Grxcr2 is required for stereocilia morphogenesis in the cochlea.

Grxcr2 是耳蜗立体纤毛形态发生所必需的

Avenarius Matthew R, Jung Jae-Yun, Askew Charles, Jones Sherri M, Hunker Kristina L, Azaiez Hela, Rehman Atteeq U, Schraders Margit, Najmabadi Hossein, Kremer Hannie, Smith Richard J H, Géléoc Gwenaëlle S G, Dolan David F, Raphael Yehoash, Kohrman David C

Transient Surface CCR5 Expression by Naive CD8+ T Cells within Inflamed Lymph Nodes Is Dependent on High Endothelial Venule Interaction and Augments Th Cell-Dependent Memory Response

炎症淋巴结内初始CD8+ T细胞的瞬时表面CCR5表达依赖于高内皮细胞与淋巴管的相互作用,并增强Th细胞依赖性记忆反应。

David Askew,Charles A Su,Deborah S Barkauskas,R Dixon Dorand,Jay Myers,Rachel Liou,Joseph Nthale,Alex Y Huang

Tmc gene therapy restores auditory function in deaf mice

TMC基因疗法可恢复聋小鼠的听觉功能

Askew, Charles; Rochat, Cylia; Pan, Bifeng; Asai, Yukako; Ahmed, Hena; Child, Erin; Schneider, Bernard L; Aebischer, Patrick; Holt, Jeffrey R

Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice

PDZD7基因缺失会破坏耳蜗毛细胞中的Usher综合征2型蛋白复合物,导致小鼠听力丧失。

Zou, Junhuang; Zheng, Tihua; Ren, Chongyu; Askew, Charles; Liu, Xiao-Ping; Pan, Bifeng; Holt, Jeffrey R; Wang, Yong; Yang, Jun

The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs.

出生后连接 E-钙黏蛋白的积累与哺乳动物平衡器官中支持细胞直接转化为感觉毛细胞的能力呈负相关

Collado Maria Sol, Thiede Benjamin R, Baker Wendy, Askew Charles, Igbani Lisa M, Corwin Jeffrey T

Localization and expression of clarin-1, the Clrn1 gene product, in auditory hair cells and photoreceptors.

Clrn1 基因产物 clarin-1 在听觉毛细胞和感光细胞中的定位和表达

Zallocchi Marisa, Meehan Daniel T, Delimont Duane, Askew Charles, Garige Suneetha, Gratton Michael Anne, Rothermund-Franklin Christie A, Cosgrove Dominic