日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MCT1 lactate transporter blockade re-invigorates anti-tumor immunity through metabolic rewiring of dendritic cells in melanoma

MCT1乳酸转运蛋白阻断通过黑色素瘤中树突状细胞的代谢重编程重新激活抗肿瘤免疫力

Niveau, Camille; Cettour-Cave, Mélanie; Mouret, Stéphane; Sosa Cuevas, Eleonora; Pezet, Mylene; Roubinet, Benoît; Gil, Hugo; De Fraipont, Florence; Landemarre, Ludovic; Charles, Julie; Saas, Philippe; Aspord, Caroline

Soluble VE-cadherin as a biomarker of response to immunotherapy by anti-PD1 in metastatic melanoma

可溶性VE-钙黏蛋白作为转移性黑色素瘤抗PD-1免疫疗法疗效的生物标志物

Broche, Clémentine; Um, Khémary; Vilgrain, Isabelle; Mouret, Stéphane; Leccia, Marie-Thérèse; Seigneurin, Arnaud; Bouillet, Laurence; Enquebecq, Marie; Salomon, Aude; Aspord, Caroline; Busser, Benoit; Porret, Pauline; Belbezier, Aude; Chaperot, Laurence; Charles, Julie

Melanoma causes phenotypic modulations and metabolic switches of iNKT cells influencing clinical outcomes

黑色素瘤会引起iNKT细胞的表型改变和代谢转换,从而影响临床结果。

Degeorges, Emmanuelle; Mouret, Stéphane; Girard, Pauline; Niveau, Camille; Cettour-Cave, Mélanie; Sosa Cuevas, Eleonora; De Fraipont, Florence; Charles, Julie; Saas, Philippe; Aspord, Caroline

HBV and HBsAg strongly reshape the phenotype, function, and metabolism of DCs according to patients' clinical stage

根据患者的临床阶段,HBV 和 HBsAg 会显著改变树突状细胞的表型、功能和代谢。

Dumolard, Lucile; Gerster, Theophile; Chuffart, Florent; Decaens, Thomas; Hilleret, Marie-Noelle; Larrat, Sylvie; Saas, Philippe; Jouvin-Marche, Evelyne; Durantel, David; Marche, Patrice N; Macek Jilkova, Zuzana; Aspord, Caroline

Circulating immune landscape in melanoma patients undergoing anti-PD1 therapy reveals key immune features according to clinical response to treatment

接受抗PD-1治疗的黑色素瘤患者的循环免疫图谱揭示了与临床治疗反应相关的关键免疫特征

Sosa Cuevas, Eleonora; Mouret, Stéphane; Vayssière, Guillaume; Kerboua, Siham; Girard, Pauline; Molens, Jean-Paul; Manceau, Marc; Charles, Julie; Saas, Philippe; Aspord, Caroline

Harnessing Immune Cell Metabolism to Modulate Alloresponse in Transplantation

利用免疫细胞代谢调节移植中的同种异体反应

Noble, Johan; Macek Jilkova, Zuzana; Aspord, Caroline; Malvezzi, Paolo; Fribourg, Miguel; Riella, Leonardo V; Cravedi, Paolo

Immune checkpoints on T and NK cells in the context of HBV infection: Landscape, pathophysiology and therapeutic exploitation

乙肝病毒感染背景下T细胞和NK细胞的免疫检查点:概况、病理生理学和治疗应用

Dumolard, Lucile; Aspord, Caroline; Marche, Patrice N; Macek Jilkova, Zuzana

A New Plasmacytoid Dendritic Cell-Based Vaccine in Combination with Anti-PD-1 Expands the Tumor-Specific CD8+ T Cells of Lung Cancer Patients

一种新型的基于浆细胞样树突状细胞的疫苗联合抗PD-1抗体可扩增肺癌患者肿瘤特异性CD8+ T细胞

Hannani, Dalil; Leplus, Estelle; Laurin, David; Caulier, Benjamin; Aspord, Caroline; Madelon, Natacha; Bourova-Flin, Ekaterina; Brambilla, Christian; Brambilla, Elisabeth; Toffart, Anne-Claire; Laulagnier, Karine; Chaperot, Laurence; Plumas, Joël

Dendritic Cell Subsets in Melanoma: Pathophysiology, Clinical Prognosis and Therapeutic Exploitation

黑色素瘤中的树突状细胞亚群:病理生理学、临床预后和治疗应用

Sosa Cuevas, Eleonora; Saas, Philippe; Aspord, Caroline

An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial

一种基于浆细胞样树突状细胞系的创新型癌症疫苗在首次人体试验中,能够启动并扩增黑色素瘤患者体内的抗肿瘤T细胞。

Charles, Julie; Chaperot, Laurence; Hannani, Dalil; Bruder Costa, Juliana; Templier, Isabelle; Trabelsi, Sabiha; Gil, Hugo; Moisan, Anaick; Persoons, Virginie; Hegelhofer, Harald; Schir, Edith; Quesada, Jean-Louis; Mendoza, Christophe; Aspord, Caroline; Manches, Olivier; Coulie, Pierre G; Khammari, Amir; Dreno, Brigitte; Leccia, Marie-Thérèse; Plumas, Joel