日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

拮抗性纳米抗体揭示了GSDMD孔道形成机制及其潜在的治疗应用。

Lisa D J Schiffelers ,Yonas M Tesfamariam ,Lea-Marie Jenster ,Stefan Diehl ,Sophie C Binder ,Sabine Normann ,Jonathan Mayr ,Steffen Pritzl ,Elena Hagelauer ,Anja Kopp ,Assaf Alon ,Matthias Geyer ,Hidde L Ploegh ,Florian I Schmidt

AlphaFold2 structures template ligand discovery

AlphaFold2 结构模板配体发现

Jiankun Lyu, Nicholas Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish K Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey DiBerto, Kuglae Kim, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Brya

The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination

SpoVA 膜复合物是孢子形成过程中吡啶二羧酸的输入和发芽过程中吡啶二羧酸的输出所必需的

Yongqiang Gao, Rocio Del Carmen Barajas-Ornelas, Jeremy D Amon, Fernando H Ramírez-Guadiana, Assaf Alon, Kelly P Brock, Debora S Marks, Andrew C Kruse, David Z Rudner

Structures of the σ2 receptor enable docking for bioactive ligand discovery

σ2 受体的结构有助于对接以发现生物活性配体

Assaf Alon #, Jiankun Lyu #, Joao M Braz #, Tia A Tummino, Veronica Craik, Matthew J O'Meara, Chase M Webb, Dmytro S Radchenko, Yurii S Moroz, Xi-Ping Huang, Yongfeng Liu, Bryan L Roth, John J Irwin, Allan I Basbaum, Brian K Shoichet, Andrew C Kruse

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

布氏锥虫中的剪接前导 RNA 沉默 (SLS) 通路由内质网、高尔基复合体或线粒体蛋白质因子的扰动诱导:SLS 诱导激酶 PK3 的功能分析

Uthman Okalang #, Bar Mualem Bar-Ner #, K Shanmugha Rajan #, Nehemya Friedman, Saurav Aryal, Katarina Egarmina, Ronen Hope, Netaly Khazanov, Hanoch Senderowitz, Assaf Alon, Deborah Fass, Shulamit Michaeli

Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596

探索巨型病毒中的 ORFan 结构域:巨型病毒巯基氧化酶 R596 的结构

Motti Hakim, Daria Ezerina, Assaf Alon, Ohad Vonshak, Deborah Fass