日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting human plasma cells using regulated BCMA CAR T cells eliminates circulating antibodies in humanized mice.

利用调控的BCMA CAR T细胞靶向人类浆细胞,可消除人源化小鼠体内的循环抗体

Honaker Yuchi, Gruber David, Jacobs Chester, Yu-Hong Cheng Rene, Patel Shivani, Galvan Christopher Zavala, Khan Iram F, Zhou Kevin, Sommer Karen, Astrakhan Alexander, Cook Peter J, James Richard G, Rawlings David J

Sensitive and adaptable pharmacological control of CAR T cells through extracellular receptor dimerization

通过细胞外受体二聚化对CAR T细胞进行灵敏且可适应的药理学控制

Leung, Wai-Hang; Gay, Joel; Martin, Unja; Garrett, Tracy E; Horton, Holly M; Certo, Michael T; Blazar, Bruce R; Morgan, Richard A; Gregory, Philip D; Jarjour, Jordan; Astrakhan, Alexander

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome

造血谱系中普遍存在的高水平基因表达为小鼠Wiskott-Aldrich综合征的慢病毒基因治疗提供了有效途径。

Astrakhan, Alexander; Sather, Blythe D; Ryu, Byoung Y; Khim, Socheath; Singh, Swati; Humblet-Baron, Stephanie; Ochs, Hans D; Miao, Carol H; Rawlings, David J

Antiplatelet antibodies in WASP(-) mice correlate with evidence of increased in vivo platelet consumption

WASP(-)小鼠体内抗血小板抗体的存在与体内血小板消耗增加的证据相关。

Marathe, Bindumadhav M; Prislovsky, Amanda; Astrakhan, Alexander; Rawlings, David J; Wan, Jim Y; Strom, Ted S