Syringic and ascorbic acids prevent NDMA-induced pulmonary fibrogenesis, inflammation, apoptosis, and oxidative stress through the regulation of PI3K-Akt/PKB-mTOR-PTEN signaling pathway
丁香酸和抗坏血酸通过调节PI3K-Akt/PKB-mTOR-PTEN信号通路,预防NDMA诱导的肺纤维化、炎症、细胞凋亡和氧化应激。
期刊:Metabolism Open
影响因子:2.7
doi:10.1016/j.metop.2022.100179
Somade, Oluwatobi T; Adeyi, Olubisi E; Ajayi, Babajide O; Asunde, Osiro O; Iloh, Precious D; Adesanya, Adedayo A; Babalola, Olanrewaju I; Folorunsho, Oluwaseyi T; Olakunle, Deborah A; Lawal, Opeyemi F
凋亡
炎症
表观遗传
mTOR
氧化应激
炎症/感染
信号转导
PTEN
细胞生物学
毒理研究