日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mechanistic modeling of cell viability assays with in silico lineage tracing

利用计算机模拟谱系追踪对细胞活力检测进行机制建模

Mutsuddy, Arnab; Huggins, Jonah R; Amrit, Aurore K; Harley-Gasaway, Atalanta Manuela; Erdem, Cemal; Jones, Evan T; Laurine, Olivia G; Calhoun, Jon C; Birtwistle, Marc R

A Phase 1, Multicenter, Open-Label Study to Evaluate the Pharmacokinetics of Iberdomide in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared with Healthy Subjects

一项 1 期、多中心、开放标签研究,旨在评估伊比度胺在轻度、中度或重度肝功能损害受试者与健康受试者中的药代动力学差异。

Cheng, Yiming; Ye, Ying; Gaudy, Allison; Ghosh, Atalanta; Xue, Yongjun; Wang, Alice; Zhou, Simon; Li, Yan

CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial

CC-90001(一种 c-Jun N 端激酶 (JNK) 抑制剂)治疗肺纤维化患者的 II 期随机、安慰剂对照试验设计

Popmihajlov, Zoran; Sutherland, Donna J; Horan, Gerald S; Ghosh, Atalanta; Lynch, David A; Noble, Paul W; Richeldi, Luca; Reiss, Theodore F; Greenberg, Steven

Multiple-Dose Pharmacokinetics of Ozanimod and its Major Active Metabolites and the Pharmacodynamic and Pharmacokinetic Interactions with Pseudoephedrine, a Sympathomimetic Agent, in Healthy Subjects

在健康受试者中,多次给药后奥扎尼莫德及其主要活性代谢物的药代动力学,以及与拟交感神经药伪麻黄碱的药效学和药代动力学相互作用

Tran, Jonathan Q; Zhang, Peijin; Walker, Susan; Ghosh, Atalanta; Syto, Mary; Wang, Xiaomin; Harris, Sarah; Palmisano, Maria

Exosite 1 thrombin inhibition with JNJ-64179375 inhibits thrombus formation in a human translational model of thrombosis

使用 JNJ-64179375 抑制外位点 1 凝血酶可抑制人类血栓形成转化模型中的血栓形成

Simon J Wilson, Thomas M Connolly, Gary Peters, Atalanta Ghosh, Maureen Johnson, David E Newby

Outpatient versus inpatient mixed meal tolerance and arginine stimulation testing yields comparable measures of variability for assessment of beta cell function

门诊与住院患者的混合餐耐受性和精氨酸刺激试验在评估β细胞功能方面可得出相似的变异性指标。

Shankar, Sudha S; Lee, Douglas S; Raymond, Ralph H; Calle, Roberto A; Cobelli, Claudio; Ghosh, Atalanta; Robertson, R Paul; Ruetten, Hartmut; Staten, Myrlene A; Stefanovski, Darko; Vella, Adrian; Whitaker, Sanya; Fryburg, David A

Validation of a novel method for determining the renal threshold for glucose excretion in untreated and canagliflozin-treated subjects with type 2 diabetes mellitus

验证一种测定未经治疗和接受卡格列净治疗的2型糖尿病患者肾脏葡萄糖排泄阈值的新方法

Polidori, David; Sha, Sue; Ghosh, Atalanta; Plum-Mörschel, Leona; Heise, Tim; Rothenberg, Paul

Canagliflozin lowers postprandial glucose and insulin by delaying intestinal glucose absorption in addition to increasing urinary glucose excretion: results of a randomized, placebo-controlled study

卡格列净通过延缓肠道对葡萄糖的吸收并增加尿糖排泄,从而降低餐后血糖和胰岛素水平:一项随机、安慰剂对照研究的结果

Polidori, David; Sha, Sue; Mudaliar, Sunder; Ciaraldi, Theodore P; Ghosh, Atalanta; Vaccaro, Nicole; Farrell, Kristin; Rothenberg, Paul; Henry, Robert R