日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a Selective and Potent Inhibitor of Cyclin-Dependent Kinase 12/13 Employing a Noncovalent Mechanism

利用非共价机制发现一种选择性强、高效的细胞周期蛋白依赖性激酶12/13抑制剂

Swyka, Robert A; Styduhar, Evan D; Wang, Anlai; Li, Xin; Zhang, Ke; Witten, Michael R; Zhao, Peng; Liang, Michael Z; Atasoylu, Onur; He, Peng; Soderquist, Ryan; Hansbury, Mike; Huo, Lu; Chen, Haiying; Zimmer, Derek; Zhang, Wenliang; Wang, Kathy; Volgina, Alla; Epling, Leslie B; Crowgey, Erin; Kumari, Ekta; Abdollahi, Angela; Zhang, Guofeng; Rupar, Mark; Schaffer, Michael; Mayes, Patrick A; Kim, Sunkyu; Vechorkin, Oleg; Wang, Xiaozhao

Potent and Selective Biaryl Amide Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1)

高效选择性双芳基酰胺类造血祖细胞激酶1 (HPK1) 抑制剂

Sokolsky, Alexander; Vechorkin, Oleg; Hummel, Joshua R; Styduhar, Evan D; Wang, Anlai; Nguyen, Minh H; Ye, Hai Fen; Liu, Kai; Zhang, Ke; Pan, Jun; Ye, Qinda; Atasoylu, Onur; Behshad, Elham; He, Xin; Conlen, Patricia; Stump, Kristine; Ye, Min; Diamond, Sharon; Covington, Maryanne; Yeleswaram, Swamy; Yao, Wenqing

Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners

改善(+)-Discodermolide-紫杉醇杂合同系物的剂量反应关系

Nadaradjane, Celine; Yang, Chia-Ping Huang; Rodriguez-Gabin, Alicia; Ye, Kenny; Sugasawa, Keizo; Atasoylu, Onur; Smith, Amos B 3rd; Horwitz, Susan Band; McDaid, Hayley M

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

HIF 脯氨酰羟化酶抑制剂在临床试验中的分子和细胞机制

Tzu-Lan Yeh, Thomas M Leissing, Martine I Abboud, Cyrille C Thinnes, Onur Atasoylu, James P Holt-Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T Lohans, Ivanhoe K H Leung, Helen Morcrette, Ian J Clifton, Timothy D W Claridge, Akane Kawamura, Emily Flashman, Xin Lu, Peter J Ratcliffe

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

具有小鼠脑内活性的强效选择性三唑类缺氧诱导因子脯氨酰羟化酶抑制剂

Mun Chiang Chan, Onur Atasoylu, Emma Hodson, Anthony Tumber, Ivanhoe K H Leung, Rasheduzzaman Chowdhury, Verónica Gómez-Pérez, Marina Demetriades, Anna M Rydzik, James Holt-Martyn, Ya-Min Tian, Tammie Bishop, Timothy D W Claridge, Akane Kawamura, Christopher W Pugh, Peter J Ratcliffe, Christopher J

Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned

(+)-海绵抑素 1 微型形式的设计、合成和生物学评价:经验教训

Smith, Amos B 3rd; Risatti, Christina A; Atasoylu, Onur; Bennett, Clay S; Liu, Junke; Cheng, Hongsheng; TenDyke, Karen; Xu, Qunli

Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity

设计并合成(+)-discodermolide-紫杉醇杂合物,以增强其生物活性。

Smith, Amos B; Sugasawa, Keizo; Atasoylu, Onur; Yang, Chia-Ping Huang; Horwitz, Susan Band

Tetrazine phototriggers: probes for peptide dynamics

四嗪光触发剂:肽动力学探针

Tucker, Matthew J; Courter, Joel R; Chen, Jianxin; Atasoylu, Onur; Smith, Amos B 3rd; Hochstrasser, Robin M

The solution structure of (+)-spongistatin 1 in DMSO

(+)-海绵抑素 1 在 DMSO 中的溶液结构

Atasoylu, Onur; Furst, George; Risatti, Christina; Smith, Amos B 3rd

Design, synthesis, and biological evaluation of EF- and ABEF- analogues of (+)-spongistatin 1

(+)-海绵抑素 1 的 EF 和 ABEF 类似物的设计、合成和生物学评价

Smith, Amos B 3rd; Risatti, Christina A; Atasoylu, Onur; Bennett, Clay S; Tendyke, Karen; Xu, Qunli