Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD
Sestrin-2 是 PDGFRβ 信号传导的抑制剂，可促进小鼠因吸烟引起的肺气肿，并且在 COPD 患者中上调
期刊:Disease Models & Mechanisms
影响因子:4
doi:10.1242/dmm.013482
Juliana Heidler, Athanasios Fysikopoulos, Frank Wempe, Michael Seimetz, Thorsten Bangsow, Ana Tomasovic, Florian Veit, Susan Scheibe, Alexandra Pichl, Friederike Weisel, K C Kent Lloyd, Peter Jaksch, Walter Klepetko, Norbert Weissmann, Harald von Melchner
