日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

雷帕霉素在老年犬中的应用试验(TRIAD):一项前瞻性、平行组、双盲、随机、安慰剂对照、多中心试验的研究设计和原理,该试验旨在评估雷帕霉素对来自犬衰老项目的健康中年犬的疗效。

Coleman, Amanda E; Creevy, Kate E; Anderson, Rozalyn; Reed, May J; Fajt, Virginia R; Aicher, Kathleen M; Atiee, Genna; Barnett, Brian G; Baumwart, Ryan D; Boudreau, Beth; Cunningham, Suzanne M; Dunbar, Matthew D; Ditzler, Bobbie; Ferguson, Anna M; Forsyth, Kiersten K; Gambino, Anya N; Gordon, Sonya G; Hammond, Hillary K; Holland, Sydney N; Iannaccone, Mary K; Illing, Kate; Kadotani, Saki; Knowles, Shelby A; MacLean, Evan L; Maran, Brian A; Markovic, Lauren E; McGrath, Stephanie; Melvin, Rachel L; Mueller, Mikaela S; Nelson, O Lynne; Olby, Natasha J; Pancotto, Theresa E; Parsley, Elizabeth; Potter, Brianna M; Prescott, Jena O; Saunders, Ashley B; Sawyer, Holly M; Scansen, Brian A; Schmid, Sarah M; Smith, Courtney C; Tjostheim, Sonja S; Tolbert, M Katherine; Tropf, Melissa A; Visser, Lance C; Ward, Jessica L; Wesselowski, Sonya R; Windsor, Rebecca C; Yang, Vicky K; Ruple, Audrey; Promislow, Daniel E L; Kaeberlein, Matt

Thoracic radiographic findings in cats with feline infectious peritonitis

猫传染性腹膜炎的胸部X线检查结果

Repyak, Kristin; Atiee, Genna; Cook, Audrey; Bryan, Laura; Gremillion, Christine

Population pharmacokinetic rationale for intravenous contezolid acefosamil followed by oral contezolid dosage regimens

静脉注射康泰唑胺磷酸盐,然后口服康泰唑胺给药方案的群体药代动力学原理

Jürgen B Bulitta, Edward Fang, Martin E Stryjewski, Wen Wang, George J Atiee, Jeffrey G Stark, Barry Hafkin

A phase I, first-in-human study to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics of MRG-001 in healthy subjects

一项 I 期首次人体试验,旨在评估 MRG-001 在健康受试者中的安全性、耐受性、药代动力学和药效学。

Ali R Ahmadi ,George Atiee ,Bart Chapman ,Laurie Reynolds ,John Sun ,Andrew M Cameron ,Russell N Wesson ,James F Burdick ,Zhaoli Sun

A Phase 1 pharmacokinetic study of a single-dose bioadhesive clindamycin 2% gel for bacterial vaginosis

一项针对细菌性阴道炎的单剂量2%生物粘附性克林霉素凝胶的I期药代动力学研究

Mauck, Christine K; Atiee, George J; McCulloh, Jennifer; Reynolds, Laurie; Zack, Nadene; Friend, David R

Improved Speech Intelligibility in Subjects With Stable Sensorineural Hearing Loss Following Intratympanic Dosing of FX-322 in a Phase 1b Study

在一项 1b 期研究中,鼓室内注射 FX-322 后,稳定型感音神经性听力损失患者的言语清晰度得到改善。

McLean, Will J; Hinton, Ashley S; Herby, Jenna T J; Salt, Alec N; Hartsock, Jared J; Wilson, Sam; Lucchino, David L; Lenarz, Thomas; Warnecke, Athanasia; Prenzler, Nils; Schmitt, Heike; King, Susan; Jackson, Lance E; Rosenbloom, Jeffrey; Atiee, George; Bear, Moraye; Runge, Christina L; Gifford, René H; Rauch, Steven D; Lee, Daniel J; Langer, Robert; Karp, Jeffrey M; Loose, Christopher; LeBel, Carl

Comparing the Pharmacokinetics of 2 Novel Intravenous Tramadol Dosing Regimens to Oral Tramadol: A Randomized 3-Arm Crossover Study

比较两种新型静脉曲马多给药方案与口服曲马多的药代动力学:一项随机 3 组交叉研究

Lucy Lu, Michael Ryan, Mark Harnett, George J Atiee, Scott A Reines

A Prospective Multicenter Evaluation of the Accuracy of a Novel Implanted Continuous Glucose Sensor: PRECISE II

一项前瞻性多中心研究评估新型植入式连续血糖传感器的准确性:PRECISE II

Christiansen, Mark P; Klaff, Leslie J; Brazg, Ronald; Chang, Anna R; Levy, Carol J; Lam, David; Denham, Douglas S; Atiee, George; Bode, Bruce W; Walters, Steven J; Kelley, Lynne; Bailey, Timothy S

Lack of Impact by SCY-078, a First-in-Class Oral Fungicidal Glucan Synthase Inhibitor, on the Pharmacokinetics of Rosiglitazone, a Substrate for CYP450 2C8, Supports the Low Risk for Clinically Relevant Metabolic Drug-Drug Interactions

SCY-078(一种首创的口服抗真菌葡聚糖合成酶抑制剂)对 CYP450 2C8 底物罗格列酮的药代动力学无影响,这表明其发生具有临床意义的代谢性药物相互作用的风险较低。

Wring, Stephen; Murphy, Gail; Atiee, George; Corr, Christy; Hyman, Michele; Willett, Michael; Angulo, David

First-in-human assessment of PRX002, an anti-α-synuclein monoclonal antibody, in healthy volunteers

在健康志愿者中首次对抗α-突触核蛋白单克隆抗体PRX002进行人体评估

Schenk, Dale B; Koller, Martin; Ness, Daniel K; Griffith, Sue G; Grundman, Michael; Zago, Wagner; Soto, Jay; Atiee, George; Ostrowitzki, Susanne; Kinney, Gene G