日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

苯乙双胍(而非二甲双胍)通过细胞自主性AMPK激活延缓T细胞急性淋巴细胞白血病/淋巴瘤的发展

Vara-Ciruelos, Diana; Dandapani, Madhumita; Russell, Fiona M; Grzes, Katarzyna M; Atrih, Abdelmadjid; Foretz, Marc; Viollet, Benoit; Lamont, Douglas J; Cantrell, Doreen A; Hardie, D Grahame

The Ancient Drug Salicylate Indirectly Targets Fructose-1,6-Bisphosphatase to Suppress Liver Glucose Production in Diet-Induced Obese Mice.

古代药物水杨酸盐通过间接靶向果糖-1,6-二磷酸酶来抑制饮食诱导肥胖小鼠的肝脏葡萄糖生成

Nisr Raid B, Atrih Abdelmadjid, Lara Erika J Gutierrez, Lamont Douglas, Luda Katarzyna M, McCrimmon Rory J, Sakamoto Kei, Rena Graham, McNeilly Alison D

An ISR-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation

GCN2 的 ISR 独立作用可防止过度核糖体生物合成和 mRNA 翻译

Mónica Román-Trufero, Istvan T Kleijn, Kevin Blighe, Jinglin Zhou, Paula Saavedra-García, Abigail Gaffar, Marilena Christoforou, Axel Bellotti, Joel Abrahams, Abdelmadjid Atrih, Douglas Lamont, Marek Gierlinski, Pooja Jayaprakash, Audrey M Michel, Eric O Aboagye, Mariia Yuneva, Glenn R Masson, Vahid

Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

细胞凋亡过程中半胱天冬酶的切割和能量传感器AMPK-α1的核滞留

Anees Rahman Cheratta ,Faisal Thayyullathil ,Simon A Hawley ,Fiona A Ross ,Abdelmajdid Atrih ,Douglas J Lamont ,Siraj Pallichankandy ,Karthikeyan Subburayan ,Ameer Alakkal ,Rachid Rezgui ,Alex Gray ,D Grahame Hardie ,Sehamuddin Galadari

DIA label-free proteomic analysis of murine bone-marrow-derived macrophages

小鼠骨髓来源巨噬细胞的 DIA 无标记蛋白质组学分析

Christa P Baker, Iain R Phair, Alejandro J Brenes, Abdelmadjid Atrih, Dylan G Ryan, Roland Bruderer, Albena T Dinkova-Kostova, Douglas J Lamont, J Simon C Arthur, Andrew J M Howden

Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1

醛缩酶是低血糖和高血糖的传感器,与 AMPK 和 mTORC1 相连。

Li, Mengqi; Zhang, Chen-Song; Feng, Jin-Wei; Wei, Xiaoyan; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Hawley, Simon A; Atrih, Abdelmadjid; Lamont, Douglas J; Wang, Zhichao; Piao, Hai-Long; Hardie, D Grahame; Lin, Sheng-Cai

Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation

RNA 帽甲基转移酶 RNMT 的上调在 T 细胞活化过程中驱动核糖体的生物合成

Alison Galloway, Aneesa Kaskar, Dimitrinka Ditsova, Abdelmadjid Atrih, Harunori Yoshikawa, Carolina Gomez-Moreira, Olga Suska, Marcin Warminski, Renata Grzela, Angus I Lamond, Edward Darzynkiewicz, Jacek Jemielity, Victoria H Cowling

SMN Depleted Mice Offer a Robust and Rapid Onset Model of Nonalcoholic Fatty Liver Disease

SMN 缺失小鼠可作为非酒精性脂肪肝疾病的稳健且快速发病模型

Marc-Olivier Deguise, Chantal Pileggi, Yves De Repentigny, Ariane Beauvais, Alexandra Tierney, Lucia Chehade, Jean Michaud, Maica Llavero-Hurtado, Douglas Lamont, Abdelmadjid Atrih, Thomas M Wishart, Thomas H Gillingwater, Bernard L Schneider, Mary-Ellen Harper, Simon H Parson, Rashmi Kothary

Mechanism of Activation of AMPK by Cordycepin

虫草素激活AMPK的机制

Simon A Hawley, Fiona A Ross, Fiona M Russell, Abdelmadjid Atrih, Douglas J Lamont, D Grahame Hardie

CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures

CAP-MAP:分析物处理最少的帽分析协议,一种快速、灵敏的分析 mRNA 帽结构的方法

Alison Galloway, Abdelmadjid Atrih, Renata Grzela, Edward Darzynkiewicz, Michael A J Ferguson, Victoria H Cowling