日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70232
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri A; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
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Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signaling, in Aged Hippocampus

鼻内给予人神经干细胞来源的细胞外囊泡疗法可以抑制老年海马体中炎症性小胶质细胞的转录组以及NLRP3和cGAS-STING信号通路

期刊:
影响因子:
doi:10.1101/2025.03.02.641082
Madhu, Leelavathi N; Kodali, Maheedhar; Rao, Shama; Attaluri, Sahithi; Upadhya, Raghavendra; Shankar, Goutham; Shuai, Bing; Somayaji, Yogish; Ganesh, Shruthi V; Kumar, Vignesh S; James, Jeswin E; Shetty, Padmashri; LeMaire, Avery; Rao, Xiaolan; Cai, James J; Shetty, Ashok K
胶质细胞
发育与干细胞
炎症
炎症/感染
信号转导
STING
cGAS-STING
LRP3
Human
干细胞
NLRP3
囊泡
细胞生物学
Hippo
发表日期：2026
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Transcriptomic and epigenetic analysis of various cell types affected by amyloid‐beta oligomers in the hippocampus of mice during aging

对衰老小鼠海马中受β-淀粉样蛋白寡聚体影响的各种细胞类型的转录组学和表观遗传学分析

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.14398
Kodali, Maheedhar; Madhu, Leelavathi N; Somayaji, Yogish; Attaluri, Sahithi; Huard, Charles; Panda, Prashanta Kumar; Shankar, Goutham; Rao, Shama; Shuai, Bing; Gonzalez, Jenny J; Oake, Chris; Hering, Catherine; Babu, Roshni Sara; Kotian, Sanya; Shetty, Ashok K; Leduc, Klarissa
细胞生物学
衰老
表观遗传
发表日期：2025
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Corrigendum: Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf War Illness

更正：在海湾战争综合征模型中，脑特异性白三烯信号传导增加伴随慢性神经炎症和认知障碍。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1557065
Attaluri, Sahithi; Upadhya, Raghavendra; Kodali, Maheedhar; Madhu, Leelavathi N; Upadhya, Dinesh; Shuai, Bing; Shetty, Ashok K
炎症
炎症/感染
信号转导
神经科学
神经炎症
发表日期：2025
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Intranasal delivery of metformin using metal-organic framework (MOF)-74-Mg nanocarriers.

利用金属有机框架（MOF）-74-Mg纳米载体进行二甲双胍的鼻内递送

期刊:Advanced Composites and Hybrid Materials
影响因子:
doi:10.1007/s42114-025-01227-y
Yuan Muzhaozi, Han Zongsu, Somayaji Yogish, Nguyen Nguyen, Hu Hanwen, Madhu Leelavathi N, Attaluri Sahithi, Kodali Maheedhar, Yang Yihao, Hsu Yu-Chuan, Ahuja Avik, Srinivasan Rahul, Pellois Jean-Philippe, Zhou Hong-Cai, Shetty Ashok K, Wang Ya
发表日期：2025
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Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.

人诱导多能干细胞衍生的神经干细胞产生的细胞外囊泡可减轻阿尔茨海默病中与疾病相关的小胶质细胞内的促炎级联反应

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.12519
Madhu Leelavathi N, Kodali Maheedhar, Upadhya Raghavendra, Rao Shama, Somayaji Yogish, Attaluri Sahithi, Shuai Bing, Kirmani Maha, Gupta Shreyan, Maness Nathaniel, Rao Xiaolan, Cai James J, Shetty Ashok K
神经科学
囊泡
发表日期：2024
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Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model

鼻内给药的源自hiPSC的神经干细胞来源的细胞外囊泡可改变活化小胶质细胞的转录组谱，并在阿尔茨海默病模型中维持脑功能。

期刊:
影响因子:
doi:10.1101/2024.01.18.576313
Madhu, Leelavathi N; Kodali, Maheedhar; Upadhya, Raghavendra; Rao, Shama; Shuai, Bing; Somayaji, Yogish; Attaluri, Sahithi; Kirmani, Maha; Gupta, Shreyan; Maness, Nathaniel; Rao, Xiaolan; Cai, James; Shetty, Ashok K
细胞生物学
发育与干细胞
神经科学
胶质细胞
阿尔茨海默症
囊泡
干细胞
发表日期：2024
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Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness

海湾战争综合征模型中，脑特异性白三烯信号传导增强伴随慢性神经炎症和认知障碍

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2022.853000
Attaluri, Sahithi; Upadhya, Raghavendra; Kodali, Maheedhar; Madhu, Leelavathi N; Upadhya, Dinesh; Shuai, Bing; Shetty, Ashok K
炎症
炎症/感染
信号转导
神经科学
神经炎症
发表日期：2022
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Moderate, intermittent voluntary exercise in a model of Gulf War Illness improves cognitive and mood function with alleviation of activated microglia and astrocytes, and enhanced neurogenesis in the hippocampus

在海湾战争综合症模型中，适度、间歇性的自愿运动可以改善认知和情绪功能，减轻小胶质细胞和星形胶质细胞的活化，并增强海马体的神经发生。

期刊:Brain Behavior and Immunity
影响因子:7.6
doi:10.1016/j.bbi.2021.07.005
Kodali, Maheedhar; Mishra, Vikas; Hattiangady, Bharathi; Attaluri, Sahithi; Gonzalez, Jenny Jaimes; Shuai, Bing; Shetty, Ashok K
胶质细胞
细胞生物学
神经科学
发表日期：2021
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Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus

中年晚期服用二甲双胍可改善认知功能，表现为减轻海马体中小胶质细胞活化和增强自噬作用。

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.13277
Kodali, Maheedhar; Attaluri, Sahithi; Madhu, Leelavathi N; Shuai, Bing; Upadhya, Raghavendra; Gonzalez, Jenny Jaimes; Rao, Xiaolan; Shetty, Ashok K
胶质细胞
细胞生物学
自噬
神经科学
发表日期：2021
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