Therapeutic effects of Lactobacillus rhamnosus, thymol and their combination against neurotoxicity in propionic acid (PA)-induced autistic rats: insights into the role of the Nrf2/HO-1, Wnt3/β-catenin/GSK3β BDNF/p-TrkB/CREB, pI3K/Akt/mTOR, AMPK/SIRT-1, and PERK/CHOP/Bcl-2 pathways
鼠李糖乳杆菌、百里香酚及其组合对丙酸（PA）诱导的自闭症大鼠神经毒性的治疗作用：对Nrf2/HO-1、Wnt3/β-catenin/GSK3β、BDNF/p-TrkB/CREB、pI3K/Akt/mTOR、AMPK/SIRT-1和PERK/CHOP/Bcl-2通路作用的深入研究
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1728908
Salem, Hoda A; Rizk, Nermin I; AbdelSalam, Moustafa H; Ahmed, Rehab; Atteia, Hebatallah Husseini; Hamdan, Ahmed M E; Alghamdi, Areej A; Alghusn, Manar A; Alatawi, Renad A; Atallah, Rawan A; Alfuhaymani, Maryam M; Alqahtani, Hatun A; Abu-Elfotuh, Karema
Bcl-2
Trk
mTOR
信号转导
自闭症
HOP
Wnt/β-Catenin
神经科学
MAPK/ERK
CHOP
Rat
CREB
GSK3
BDNF
AMPK
毒理研究
PERK
