日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dicer1 Depletion Leads to DNA Damage Accumulation and Cell Death in a RET/PTC3 Papillary Thyroid Cancer Mouse Model, Thereby Inhibiting Tumor Progression

Dicer1 缺失导致 RET/PTC3 乳头状甲状腺癌小鼠模型中 DNA 损伤积累和细胞死亡,从而抑制肿瘤进展。

Maria Rojo-Pardillo ,Alice Augenlicht ,Geneviève Dom ,Jukka Kero ,Bernard Robaye ,Carine Maenhaut

Diet links gut chemistry with cancer risk in C57Bl/6 mice and human colorectal cancer patients

饮食与C57Bl/6小鼠和人类结直肠癌患者的肠道化学物质和癌症风险相关

Cohen, Ziv; Choi, Jiahn; Peregrina, Karina; Khan, Saad; Wolfson, Sarah; Sherman, Cherrie; Augenlicht, Leonard; Kelly, Libusha

Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation

在炎症背景下,非干细胞谱系可能是肠道肿瘤发生的另一种起源。

Mathijs P Verhagen ,Rosalie Joosten ,Mark Schmitt ,Niko Välimäki ,Andrea Sacchetti ,Kristiina Rajamäki ,Jiahn Choi ,Paola Procopio ,Sara Silva ,Berdine van der Steen ,Thierry P P van den Bosch ,Danielle Seinstra ,Annemarie C de Vries ,Michail Doukas ,Leonard H Augenlicht ,Lauri A Aaltonen ,Riccardo Fodde

Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges

肠道干细胞:在环境挑战下,维持健康和衰老过程中体内平衡的守护者

Choi, Jiahn; Augenlicht, Leonard H

Combined inhibition of MTAP and MAT2a mimics synthetic lethality in tumor models via PRMT5 inhibition

MTAP 和 MAT2a 的联合抑制可通过 PRMT5 抑制模拟肿瘤模型中的合成致死率

Gabriel T Bedard, Nord Gilaj, Karina Peregrina, Isabella Brew, Elena Tosti, Karl Shaffer, Peter C Tyler, Winfried Edelmann, Leonard H Augenlicht, Vern L Schramm

Intestinal stem cell aging at single-cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics

单细胞分辨率的肠道干细胞衰老:转录扰动改变细胞发育轨迹,被老年疗法逆转

Jiahn Choi, Michele Houston, Ruixuan Wang, Kenny Ye, Wenge Li, Xusheng Zhang, Derek M Huffman, Leonard H Augenlicht

Dynamic Intestinal Stem Cell Plasticity and Lineage Remodeling by a Nutritional Environment Relevant to Human Risk for Tumorigenesis

与人类肿瘤发生风险相关的营养环境对肠道干细胞的动态可塑性和谱系重塑

Jiahn Choi #, Xusheng Zhang #, Wenge Li #, Michele Houston, Karina Peregrina, Robert Dubin, Kenny Ye, Leonard Augenlicht

EOGT enables residual Notch signaling in mouse intestinal cells lacking POFUT1

EOGT 可使缺乏 POFUT1 的小鼠肠细胞中残留的 Notch 信号传导

Mohd Nauman, Shweta Varshney, Jiahn Choi, Leonard H Augenlicht, Pamela Stanley

Unraveling the Roles of miR-204-5p and HMGA2 in Papillary Thyroid Cancer Tumorigenesis

揭示 miR-204-5p 和 HMGA2 在甲状腺乳头状癌肿瘤发生中的作用

Cindy Van Branteghem, Alice Augenlicht, Pieter Demetter, Ligia Craciun, Carine Maenhaut

The origin of intestinal cancer in the context of inflammation

炎症背景下肠癌的起源

Verhagen, Mathijs P; Joosten, Rosalie; Schmitt, Mark; Valimaki, Niko; Sacchetti, Andrea; Rajamaki, Kristiina; Choi, Jiahn; Procopio, Paola; Silva, Sara; van der Steen, Berdine; van den Bosch, Thierry P P; Seinstra, Danielle; Doukas, Michail; Augenlicht, Leonard H; Aaltonen, Lauri A; Fodde, Riccardo