A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unprotected Sex (CHARM-02)
一项 1 期随机、双盲试验比较了三种候选替诺福韦 1% 凝胶直肠杀菌剂制剂的药代动力学和结肠分布,并模拟了无保护性行为(CHARM-02)。
期刊:Aids Research and Human Retroviruses
影响因子:1.1
doi:10.1089/AID.2015.0098
Hiruy, Hiwot; Fuchs, Edward J; Marzinke, Mark A; Bakshi, Rahul P; Breakey, Jennifer C; Aung, Wutyi S; Manohar, Madhuri; Yue, Chen; Caffo, Brian S; Du, Yong; Abebe, Kaleab Z; Spiegel, Hans M L; Rohan, Lisa C; McGowan, Ian; Hendrix, Craig W