日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Vacuolar-ATPase inhibitors are antimicrobial agents active against intracellular mycobacteria

液泡ATPase抑制剂是具有抗细胞内分枝杆菌活性的抗菌剂。

Rankine-Wilson, Leah; Shapira, Tirosh; Felker, Jake; Christofferson, Matthew; Sahile, Henok; Chao, Joseph; Afshar, Houria; Andersen, Raymond J; Sun, Jim; Av-Gay, Yossef

Saskemycin, a potent and selective antimycobacterial agent targeting a unique site on the ribosome.

Saskemycin 是一种强效且选择性的抗分枝杆菌药物,靶向核糖体上的独特位点。

Wright Gerard, Cook Michael, Xu Min, Morici Martino, Travin Dmitrii, Wang Wenliang, Klepacki Dorota, Chhabra Nandini, Rao Vishwas, Sahile Henok, Hackenberger Dirk, Safdari Haaris, Berger Max, Corazza Martina, Bond Austin, Guitor Allison, Tertigas Dominique, Wang Lijun, Schaenzer Adam, Ejim Linda, Yarlagadda Venkateswarlu, Gomez James, Surette Michael, Av-Gay Yossef, Dhar Neeraj, Hung Deborah, Vázquez-Laslop Nora, Mankin Alexander, Wilson Daniel

The Parkinson's drug benztropine possesses histamine receptor 1-dependent host-directed antimicrobial activity against Mycobacterium tuberculosis.

帕金森病药物苯扎托品具有组胺受体 1 依赖性的宿主导向抗菌活性,可对抗结核分枝杆菌

Sahile Henok A, Christofferson Matthew, Alford Morgan A, Rens Celine, Haghdadi Hasti, Chao Joseph D, Langdon Georgia, Hancock Robert E W, Chen Jeffrey, Av-Gay Yossef

The diversity of clinical Mycobacterium abscessus isolates in morphology, glycopeptidolipids and infection rates in a macrophage model

临床分离的脓肿分枝杆菌在形态、糖肽脂和巨噬细胞模型感染率方面的多样性

Pichler, Virginia; Dalkilic, Lara; Shoaib, Ghazaleh; Shapira, Tirosh; Rankine-Wilson, Leah; Boudehen, Yves-Marie; Chao, Joseph D; Sexton, Danielle; Prieto, Miguel; Quon, Bradley S; Tocheva, Elitza I; Kremer, Laurent; Hsiao, William; Av-Gay, Yossef

Acidic pH modulates Burkholderia cenocepacia antimicrobial susceptibility in the cystic fibrosis nutritional environment.

囊性纤维化营养环境中的酸性 pH 值会调节伯克霍尔德氏菌对抗菌药物的敏感性

Morales L Daniela, Av-Gay Yossef, Murphy Michael E P

Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis

结核分枝杆菌胞内活性化合物及其相关靶点

Tsui, Clement K M; Sorrentino, Flavia; Narula, Gagandeep; Mendoza-Losana, Alfonso; Del Rio, Ruben Gonzalez; Herrán, Esther Pérez; Lopez, Abraham; Bojang, Adama; Zheng, Xingji; Remuiñán-Blanco, Modesto Jesus; Av-Gay, Yossef

Efficient Synthesis of Benzothiazinone Analogues with Activity against Intracellular Mycobacterium tuberculosis

高效合成具有抗细胞内结核分枝杆菌活性的苯并噻嗪酮类似物

Richter, Adrian; Narula, Gagandeep; Rudolph, Ines; Seidel, Rüdiger W; Wagner, Christoph; Av-Gay, Yossef; Imming, Peter

Whole blood RNA-seq demonstrates an increased host immune response in individuals with cystic fibrosis who develop nontuberculous mycobacterial pulmonary disease

全血RNA测序显示,患有囊性纤维化并发展为非结核分枝杆菌肺病的个体,其宿主免疫反应增强。

Prieto, Miguel Dario; Jang, Jiah; Franciosi, Alessandro N; Av-Gay, Yossef; Bach, Horacio; Tebbutt, Scott J; Quon, Bradley S

From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis

从感染微环境到治疗靶点:结核分枝杆菌的细胞内生活方式

Rankine-Wilson, Leah Isobella; Shapira, Tirosh; Sao Emani, Carine; Av-Gay, Yossef

BCG immunomodulation: From the 'hygiene hypothesis' to COVID-19

卡介苗免疫调节:从“卫生假说”到新冠肺炎

Moulson, Aaron J; Av-Gay, Yossef