日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Patient anti-FVIII drug antibodies bind preferentially to a subset of FVIII covalent states.

患者抗FVIII药物抗体优先与FVIII共价状态的子集结合

Butera Diego, Pijning Aster E, Avery Nathan G, Coxon Carmen H, Metcalfe Clive, Mimoun Angelina, Lacroix-Desmazes Sébastien, Spiegel Paul Clint Jr, Hogg Philip J

Biophysical characterization of blood coagulation factor VIII binding to lipid nanodiscs that mimic activated platelet surfaces

对模拟活化血小板表面的脂质纳米盘与血液凝固因子VIII结合的生物物理学表征

Avery, Nathan G; Young, Isabelle R; Lu, Selena; Vaughan, Jordan D; Korus, Patrick S; Richardson, Tera N; Childers, Kenneth C; Smirnov, Serge L; Spiegel, P Clint Jr

A Putative Interaction between the Transmembrane Domains of Streptococcus pyogenes Sortase A and Its Endogenous Substrate M Protein Revealed by Molecular Dynamics Simulations

分子动力学模拟揭示化脓性链球菌分选酶A跨膜结构域与其内源性底物M蛋白之间可能存在的相互作用

Avery, Nathan G; Tahti, Elise F; Spiegel, Paul Clinton; Antos, John M; McCarty, James; Amacher, Jeanine F

Atomistic Mechanism of Lipid Membrane Binding for Blood Coagulation Factor VIII with Molecular Dynamics Simulations on a Microsecond Time Scale

利用微秒时间尺度分子动力学模拟揭示血液凝固因子VIII与脂质膜结合的原子级机制

Avery, Nathan G; Childers, Kenneth C; McCarty, James; Spiegel, Paul Clinton

An interaction between the transmembrane domains of Streptococcus pyogenes sortase A and its endogenous substrate M protein revealed by molecular dynamics simulations

分子动力学模拟揭示了化脓性链球菌分选酶A跨膜结构域与其内源性底物M蛋白之间的相互作用

Avery, Nathan G; Tahti, Elise F; Spiegel, Paul Clinton; Antos, John M; McCarty, James; Amacher, Jeanine F

Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor

凝血因子VIII与患者来源的抗C1结构域抗体抑制剂结合的结构

Childers, Kenneth C; Avery, Nathan G; Estrada Alamo, Kevin A; Davulcu, Omar; Haynes, Rose Marie; Lollar, Pete; Doering, Christopher B; Coxon, Carmen H; Spiegel, P Clint

Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII.

与含磷脂酰丝氨酸的膜稳定结合需要血液凝固因子 VIII 串联 C 结构域中保守的精氨酸残基

Peters Shaun C, Childers Kenneth C, Mitchell Corbin E, Avery Nathan G, Reese Steven S Jr, Mitchell Cristopher, Wo Serena W, Swanson Christopher D, Brison Caileen M, Spiegel P Clint Jr