Pragmatic targets for moderate/severe SLE and their implications for clinical care and trial design: sustained DORIS or LLDAS for at least 6 months is sufficient while their attainment for at least 24 months ensures high specificity for damage-free progression
中重度系统性红斑狼疮的实用目标及其对临床治疗和试验设计的影响:持续至少 6 个月的 DORIS 或 LLDAS 评分即可满足治疗要求,而持续至少 24 个月则可确保对无损伤进展具有较高的特异性。
期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/ard-2023-224919
Pitsigavdaki, Sofia; Nikoloudaki, Myrto; Garantziotis, Panagiotis; Silvagni, Ettore; Repa, Argyro; Marangoni, Antonio; Flouri, Irini; Avgoustidis, Nestor; Parperis, Konstantinos; Fanouriakis, Antonis; Govoni, Marcello; Sidiropoulos, Prodromos; Boumpas, Dimitrios T; Bortoluzzi, Alessandra; Bertsias, George