日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Boosting SIV-specific CD8+ T cell responses prior to ART interruption extends time to SIVmac239 rebound.

在 ART 中断之前增强 SIV 特异性 CD8+ T 细胞反应可延长 SIVmac239 反弹的时间。

Omange Were R, Varco-Merth Benjamin D, Fadeyi Omo, Marenco Alejandra, Takata Hiroshi, Duell Derick M, Goodwin William D, Armitage Paula, Fennessey Christine M, Kose Emek, Immonen Taina T, Kosmider Ewelina, Bosche William J, Fast Randy, Homick Chris, Oswald Kelli, Shoemaker Rebecca, Bochart Rachele, MacAllister Rhonda, Labriola Caralyn S, Smedley Jeremy V, Axthelm Michael K, Edlefsen Paul T, Keele Brandon F, Lifson Jeffrey D, Gergen Janina, Petsch Benjamin, Rauch Susanne, Picker Louis J, Okoye Afam A

Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge

改良的腺病毒启动-蛋白加强免疫C亚型HIV疫苗策略可降低二级SHIV攻击后血液和组织中的病毒DNA水平

Malherbe, Delphine C; Vang, Lo; Mendy, Jason; Barnette, Philip T; Spencer, David A; Reed, Jason; Kareko, Bettie W; Sather, D Noah; Pandey, Shilpi; Wibmer, Constantinos K; Robins, Harlan; Fuller, Deborah H; Park, Byung; Lakhashe, Samir K; Wilson, James M; Axthelm, Michael K; Ruprecht, Ruth M; Moore, Penny L; Sacha, Jonah B; Hessell, Ann J; Alexander, Jeff; Haigwood, Nancy L

Molecular analysis of lymphoid tissue from rhesus macaque rhadinovirus-infected monkeys identifies alterations in host genes associated with oncogenesis.

对感染恒河猴 rhadinovirus 的猴子的淋巴组织进行分子分析,发现宿主基因发生了与肿瘤发生相关的改变

Estep Ryan Douglas, Govindan Aparna N, Manoharan Minsha, Li He, Fei Suzanne S, Park Byung S, Axthelm Michael K, Wong Scott W

Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8(+) T Cells in Nonhuman Primates

疫苗介导的抗原加工相关转运蛋白抑制不足以在非人灵长类动物中诱导主要组织相容性复合体E限制性CD8(+) T细胞

Abdulhaqq, Shaheed A; Wu, Helen; Schell, John B; Hammond, Katherine B; Reed, Jason S; Legasse, Alfred W; Axthelm, Michael K; Park, Byung S; Asokan, Aravind; Früh, Klaus; Hansen, Scott G; Picker, Louis J; Sacha, Jonah B

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

表达诺氏疟原虫抗原的巨细胞病毒载体可诱导免疫反应,从而延缓子孢子攻击后的寄生虫血症。

Hansen, Scott G; Womack, Jennie; Scholz, Isabel; Renner, Andrea; Edgel, Kimberly A; Xu, Guangwu; Ford, Julia C; Grey, Mikayla; St Laurent, Brandyce; Turner, John M; Planer, Shannon; Legasse, Al W; Richie, Thomas L; Aguiar, Joao C; Axthelm, Michael K; Villasante, Eileen D; Weiss, Walter; Edlefsen, Paul T; Picker, Louis J; Früh, Klaus

Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates

用于检测猕猴和其他非人灵长类动物结核分枝杆菌复合群感染的γ干扰素试验

Yee, JoAnn L; Prongay, Kamm; Miles, Brodie; Smedley, Jeremy; Hansen, Scott G; Axthelm, Michael K; Ardeshir, Amir; Van Rompay, Koen K A; Timmel, Gregory; Roberts, Jeffrey A

Correction: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues

更正:寨卡病毒感染恒河猴会导致病毒在多种组织中持续存在。

Hirsch, Alec J; Smith, Jessica L; Haese, Nicole N; Broeckel, Rebecca M; Parkins, Christopher J; Kreklywich, Craig; DeFilippis, Victor R; Denton, Michael; Smith, Patricia P; Messer, William B; Colgin, Lois M A; Ducore, Rebecca M; Grigsby, Peta L; Hennebold, Jon D; Swanson, Tonya; Legasse, Alfred W; Axthelm, Michael K; MacAllister, Rhonda; Wiley, Clayton A; Nelson, Jay A; Streblow, Daniel N

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

恒河猴巨细胞病毒跨物种感染食蟹猴

Burwitz, Benjamin J; Malouli, Daniel; Bimber, Benjamin N; Reed, Jason S; Ventura, Abigail B; Hancock, Meaghan H; Uebelhoer, Luke S; Bhusari, Amruta; Hammond, Katherine B; Espinosa Trethewy, Renee G; Klug, Alex; Legasse, Alfred W; Axthelm, Michael K; Nelson, Jay A; Park, Byung S; Streblow, Daniel N; Hansen, Scott G; Picker, Louis J; Früh, Klaus; Sacha, Jonah B

Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes

逃脱单克隆抗体治疗的基孔肯雅病毒在临床上已减弱,性质稳定,且无法在蚊子体内纯化。

Pal, Pankaj; Fox, Julie M; Hawman, David W; Huang, Yan-Jang S; Messaoudi, Ilhem; Kreklywich, Craig; Denton, Michael; Legasse, Alfred W; Smith, Patricia P; Johnson, Syd; Axthelm, Michael K; Vanlandingham, Dana L; Streblow, Daniel N; Higgs, Stephen; Morrison, Thomas E; Diamond, Michael S

Polyinosinic-polycytidylic acid is the most effective TLR adjuvant for SIV Gag protein-induced T cell responses in nonhuman primates.

聚肌苷酸-聚胞苷酸是用于非人灵长类动物中 SIV Gag 蛋白诱导的 T 细胞反应的最有效的 TLR 佐剂

Park Haesun, Adamson Lauren, Ha Tae, Mullen Karl, Hagen Shoko I, Nogueron Arys, Sylwester Andrew W, Axthelm Michael K, Legasse Al, Piatak Michael Jr, Lifson Jeffrey D, McElrath Juliana M, Picker Louis J, Seder Robert A