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日期影响因子

A novel commensal Neisseria species harboring the gonococcal diagnostic marker DR-9 causes false-positive Roche cobas NAAT results

一种携带淋球菌诊断标记物DR-9的新型共生奈瑟菌会导致罗氏cobas核酸扩增检测（NAAT）出现假阳性结果。

期刊:Journal of Clinical Microbiology

doi:10.1128/jcm.01022-25

Ayala, Julio C; Hutton, Shelby M; Cartee, John C; Reimche, Jennifer L; Joseph, Sandeep J; Herrod, Bridgett; LaPoint, Halie; Cao, Linda; Baldwin, Tamara; Gainey, Youli; Ermel, Aaron C; Williams, James A; Palavecino, Elizabeth; St Cyr, Sancta B; Schmerer, Matthew W; Kersh, Ellen N

发表日期：2025

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Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR

激素类固醇通过与MtrR结合，诱导淋病奈瑟菌产生多药耐药性和应激反应基因。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-024-45195-1

Hooks, Grace M; Ayala, Julio C; Holley, Concerta L; Dhulipala, Vijaya; Beggs, Grace A; Perfect, John R; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

免疫/内分泌

发表日期：2024

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Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation

淋病奈瑟菌对葡萄糖和乳酸的转录反应：对抵抗氧化损伤和生物膜形成的影响

影响因子:4.7

doi:10.1128/mbio.01761-24

Ayala, Julio C; Balthazar, Jacqueline T; Shafer, William M

发表日期：2024

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Hormonal steroids bind the Neisseria gonorrhoeae multidrug resistance regulator, MtrR, to induce a multidrug binding efflux pump and stress-response sigma factor

激素类固醇与淋病奈瑟菌多药耐药调节因子 MtrR 结合，诱导多药结合外排泵和应激反应 σ 因子的表达。

doi:10.1101/2023.06.13.544409

Hooks, Grace M; Ayala, Julio C; Beggs, Grace A; Perfect, John R; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

免疫/内分泌

发表日期：2023

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Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

基于肽的抗菌药物抑制耐药性-结节形成-细胞分裂多药外排泵的结构基础

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.02990-22

Lyu, Meinan; Ayala, Julio C; Chirakos, Isabella; Su, Chih-Chia; Shafer, William M; Yu, Edward W

细胞生物学

发表日期：2022

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Transcriptional regulation of the mtrCDE efflux pump operon: importance for Neisseria gonorrhoeae antimicrobial resistance

mtrCDE外排泵操纵子的转录调控：对淋病奈瑟菌抗菌素耐药性的重要性

期刊:Microbiology-Sgm

影响因子:3.5

doi:10.1099/mic.0.001231

Ayala, Julio C; Balthazar, Jacqueline T; Shafer, William M

发表日期：2022

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Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A

RpoB抑制剂珊瑚吡喃酮A具有强效的体外和离体抗淋球菌活性

影响因子:3.1

doi:10.1128/msphere.00362-22

Edwards, Jennifer L; Balthazar, Jacqueline T; Esposito, Danillo L A; Ayala, Julio C; Schiefer, Andrea; Pfarr, Kenneth; Hoerauf, Achim; Alt, Silke; Hesterkamp, Thomas; Grosse, Miriam; Stadler, Marc; Golparian, Daniel; Unemo, Magnus; Read, Timothy D; Shafer, William M

发表日期：2022

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Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations

淋病奈瑟菌MtrR操纵子复合物的结构揭示了DNA识别和抗生素耐药性相关临床突变的分子机制

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkab213

Beggs, Grace A; Ayala, Julio C; Kavanaugh, Logan G; Read, Timothy D; Hooks, Grace M; Schumacher, Maria A; Shafer, William M; Brennan, Richard G

发表日期：2021

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H-NS: an overarching regulator of the Vibrio cholerae life cycle.

H-NS：霍乱弧菌生命周期的总体调节因子

期刊:Research in Microbiology

影响因子:3.4

doi:10.1016/j.resmic.2016.07.007

Ayala Julio C, Silva Anisia J, Benitez Jorge A

发表日期：2017

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RNA-seq analysis identifies new genes regulated by the histone-like nucleoid structuring protein (H-NS) affecting Vibrio cholerae virulence, stress response and chemotaxis

RNA测序分析鉴定出受组蛋白样核样结构蛋白（H-NS）调控的新基因，这些基因影响霍乱弧菌的毒力、应激反应和趋化性。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0118295

Wang, Hongxia; Ayala, Julio C; Benitez, Jorge A; Silva, Anisia J

发表日期：2015

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