日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The functional dynamics of FicD's TPR domain are modulated by the interaction with ATP and BiP

FicD的TPR结构域的功能动态受ATP和BiP相互作用的调节。

Runge, Svenja; Bilgen, Ecenaz; Magni, Andrea; Bonollo, Giorgio; Colombo, Giorgio; Itzen, Aymelt; Lamb, Don C

Pronucleotide Probes Reveal a Diverging Specificity for AMPylation vs UMPylation of Human and Bacterial Nucleotide Transferases

前核苷酸探针揭示人类和细菌核苷酸转移酶的 AMPylation 与 UMPylation 具有不同的特异性

Dietrich Mostert, Wilhelm Andrei Bubeneck, Theresa Rauh, Pavel Kielkowski, Aymelt Itzen, Kirsten Jung, Stephan A Sieber

The Alarmone Diadenosine Tetraphosphate as a Cosubstrate for Protein AMPylation

报警分子二腺苷四磷酸作为蛋白质AMP化反应的共底物

Frese, Matthias; Saumer, Philip; Yuan, Yizhi; Herzog, Doreen; Höpfner, Dorothea; Itzen, Aymelt; Marx, Andreas

Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b

军团菌效应子 Lem3 的去磷酸化作用通过重塑 Rab1b 的开关 II 区域发挥作用

Marietta S Kaspers #, Vivian Pogenberg #, Christian Pett, Stefan Ernst, Felix Ecker, Philipp Ochtrop, Michael Groll, Christian Hedberg, Aymelt Itzen

The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3

DNA 结合诱导的伯氏柯克斯体 Fic 酶的 (de)AMPylation 活性靶向组蛋白 H3

Dorothea Höpfner, Adam Cichy, Vivian Pogenberg, Christoph Krisp, Soraya Mezouar, Nina C Bach, Jan Grotheer, Sandra Madariaga Zarza, Eric Martinez, Matteo Bonazzi, Matthias J Feige, Stephan A Sieber, Hartmut Schlüter, Aymelt Itzen

Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD

人类伴侣蛋白BiP的AMPylation特异性由FICD的TPR基序介导

Joel Fauser, Burak Gulen, Vivian Pogenberg, Christian Pett, Danial Pourjafar-Dehkordi, Christoph Krisp, Dorothea Höpfner, Gesa König, Hartmut Schlüter, Matthias J Feige, Martin Zacharias, Christian Hedberg, Aymelt Itzen

Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1

Legionella DrrA 的 Rab1-AMPylation 由 Rab1 变构激活

Jiqing Du #, Marie-Kristin von Wrisberg #, Burak Gulen, Matthias Stahl, Christian Pett, Christian Hedberg, Kathrin Lang, Sabine Schneider, Aymelt Itzen

Proteolysis of Rab32 by Salmonella GtgE induces an inactive GTPase conformation

沙门氏菌GtgE对Rab32的蛋白水解作用诱导其形成无活性的GTP酶构象。

Savitskiy, Sergey; Wachtel, Rudolf; Pourjafar-Dehkordi, Danial; Kang, Hyun-Seo; Trauschke, Vanessa; Lamb, Don C; Sattler, Michael; Zacharias, Martin; Itzen, Aymelt

Legionella effector AnkX displaces the switch II region for Rab1b phosphocholination

军团菌效应子 AnkX 取代开关 II 区域进行 Rab1b 磷酸胆碱化

Stefan Ernst, Felix Ecker, Marietta S Kaspers, Philipp Ochtrop, Christian Hedberg, Michael Groll, Aymelt Itzen

Conformational control of small GTPases by AMPylation

AMP化对小GTP酶构象的控制

Barthelmes, Katja; Ramcke, Evelyn; Kang, Hyun-Seo; Sattler, Michael; Itzen, Aymelt