Rational design, synthesis, and evaluation of novel polypharmacological compounds targeting Na(V)1.5, K(V)1.5, and K(2)P channels for atrial fibrillation.
针对 Na(V)1.5、K(V)1.5 和 K(2)P 通道治疗心房颤动的新型多药理化合物的合理设计、合成和评价
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.108387
Camargo-Ayala Lorena, Bedoya Mauricio, Dasà Albert, Prüser Merten, Schütte Sven, Prent-Peñaloza Luis, Adasme-Carreño Francisco, Kiper Aytug K, Rinné Susanne, Camargo-Ayala Paola Andrea, Peña-MartÃnez Paula A, Bueno-Orovio Alfonso, Varela Diego, Wiedmann Felix, Márquez Montesinos José C E, Mazola Yuliet, Venturini Whitney, Zúñiga Rafael, Zúñiga Leandro, Schmidt Constanze, Rodriguez Blanca, Ravens Ursula, Decher Niels, Gutiérrez Margarita, González Wendy
