日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Conformational Restriction of Designer Drugs Reveals Subtype-Selective and Biased CB(2) Agonists with Neuroprotective Effects.

构象限制设计药物揭示了具有神经保护作用的亚型选择性和偏向性 CB(2) 激动剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00604
Gioé-Gallo Claudia, Ortigueira Sandra, Prieto-Díaz Rubén, Contino Marialessandra, Azuaje Jhonny, Perrone Maria Grazia, Riganti Chiara, Alberga Domenico, Mangiatordi Giuseppe Felice, Andújar-Arias Antonio, García-Rey Aitor, Graziano Giovanni, Stefanachi Angela, Val Cristina, Martínez Antón Leandro, Rebassa Joan Biel, Reza David, Selas Asier, Francavilla Fabio, Paleo M Rita, García-Mera Xerardo, Loza M Isabel, Navarro Gemma, Brea José, Sotelo Eddy
神经科学
药物研究
发表日期：2025
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X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A(2A) Adenosine Receptor Antagonists

X射线晶体学和自由能计算揭示了A(2A)腺苷受体拮抗剂的结合机制

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202003788
Jespers, Willem; Verdon, Grégory; Azuaje, Jhonny; Majellaro, Maria; Keränen, Henrik; García-Mera, Xerardo; Congreve, Miles; Deflorian, Francesca; de Graaf, Chris; Zhukov, Andrei; Doré, Andrew S; Mason, Jonathan S; Åqvist, Johan; Cooke, Robert M; Sotelo, Eddy; Gutiérrez-de-Terán, Hugo
信号转导
发表日期：2020
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Computer-aided design of multi-target ligands at A(1)R, A(2A)R and PDE10A, key proteins in neurodegenerative diseases

利用计算机辅助设计针对神经退行性疾病关键蛋白 A(1)R、A(2A)R 和 PDE10A 的多靶点配体

期刊:Journal of Cheminformatics
影响因子:5.7
doi:10.1186/s13321-017-0249-4
Kalash, Leen; Val, Cristina; Azuaje, Jhonny; Loza, María I; Svensson, Fredrik; Zoufir, Azedine; Mervin, Lewis; Ladds, Graham; Brea, José; Glen, Robert; Sotelo, Eddy; Bender, Andreas
神经科学
PDE10
发表日期：2017
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Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid.

合成与表征一种结合咖啡因和二十二碳六烯酸的新型二价配体

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules22030366
Fernández-Dueñas Víctor, Azuaje Jhonny, Morató Xavier, Cordobilla Begoña, Domingo Joan Carles, Sotelo Eddy, Ciruela Francisco
发表日期：2017
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