日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Complete inhibition of β-tryptase by tetramer dissociation and active site allostery due to a single antibody residue

单个抗体残基通过四聚体解离和活性位点变构作用完全抑制β-胰蛋白酶

Maun, Henry R; Azumaya, Caleigh M; Walters, Benjamin T; Vij, Rajesh; Morando, Ashley; Loyet, Kelly M; Koerber, James T; Rohou, Alexis; Lazarus, Robert A

Molecular basis of CXC chemokine receptor 3 ligand multispecificity

CXC趋化因子受体3配体多特异性的分子基础

Bouyssou, Alexandre; Sun, Dawei; Zhou, Tricia; Smith, Shannon; Ho, Hoangdung; Johnson, Matthew; Azumaya, Caleigh; Noreng, Sigrid; Liu, Peter; Ti, Shu; Joshi, Prajakta; Tam, Christine; Yang, Ying; Janezic, Eric; Comps-Agrar, Laëtitia; Masureel, Matthieu

Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera.

VHL募集嵌合体通过化学方法诱导内质网应激传感器IRE1的降解。

Du Jin, Villemure Elisia, Johnson Matthew, Azumaya Caleigh, Gaspar Catarina J, Marsters Scot, Lawrence David, Foster Scott, Rohou Alexis, Cheung Tommy K, Rose Christopher M, Garner Thomas, Ro Soo, Clark Kevin, Beresini Maureen H, Braun Marie-Gabrielle, Rudolph Joachim, Hsu Peter, Ashkenazi Avi

Chemical catalyst manipulating cancer epigenome and transcription

化学催化剂操纵癌症表观基因组和转录

Yuki Yamanashi, Shinpei Takamaru, Atsushi Okabe, Satoshi Kaito, Yuto Azumaya, Yugo R Kamimura, Kenzo Yamatsugu, Tomoya Kujirai, Hitoshi Kurumizaka, Atsushi Iwama, Atsushi Kaneda, Shigehiro A Kawashima, Motomu Kanai

Macrocyclic Aromatic Oligoamides with Diphenyladamantane Units: Conformational Change from Folded to Open by N-Alkyl Removal

含二苯基金刚烷单元的大环芳香低聚酰胺:N-烷基脱除引起的构象变化(由折叠态到开环态)。

Maeda, Sae; Usami, Ryota; Takamatsu, Kei; Takato, Moemi; Kikkawa, Shoko; Hikawa, Hidemasa; Azumaya, Isao

Spherical Amides with C(3) Symmetry: Improved Synthetic Approach and Structural/Optical Analysis

具有C(3)对称性的球形酰胺:改进的合成方法和结构/光学分析

Koike, Daiki; Masu, Hyuma; Uno, Haruka; Kikkawa, Shoko; Hikawa, Hidemasa; Azumaya, Isao

Shared ligand-blocking mechanism but distinct conformational modulation by α5-targeting antibodies BIIG2 and MINT1526A

BIIG2 和 MINT1526A 这两种靶向 α5 的抗体具有共同的配体阻断机制,但构象调节方式不同。

Nguyen, Adam; Heim, Joel B; Cordara, Gabriele; Chan, Matthew C; Johannesen, Hedda; Charlesworth, Cristine; Li, Ming; Azumaya, Caleigh M; Madden, Benjamin; Krengel, Ute; Meves, Alexander; Campbell, Melody G

Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40

利用天然存在的蛋白笼铁蛋白来调节 OX40 的内在激动作用

Whitney Shatz-Binder, Caleigh M Azumaya, Brandon Leonard, Ivan Vuong, Jawahar Sudhamsu, Alexis Rohou, Peter Liu, Wendy Sandoval, Karenna Bol, Saeed Izadi, Patrick G Holder, Craig Blanchette, Remo Perozzo, Robert F Kelley, Yogeshvar Kalia

The structural basis for HIV-1 Vif antagonism of human APOBEC3G

HIV-1 Vif 拮抗人类 APOBEC3G 的结构基础

Yen-Li Li, Caroline A Langley, Caleigh M Azumaya, Ignacia Echeverria, Nicholas M Chesarino, Michael Emerman, Yifan Cheng, John D Gross

Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI

IIS 型限制性内切酶 PaqCI 的结构、活性和机制

Madison A Kennedy, Christopher J Hosford, Caleigh M Azumaya, Yvette A Luyten, Minyong Chen, Richard D Morgan, Barry L Stoddard