日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells

20q11.21 扩增子在 hPSC 和分化肝细胞植入模型中的体内致瘤性

Chris S Pridgeon, Shiva Seyed Forootan, Fang Zhang, Nicholas Harper, Daniel Palmer, Richard Weightmann, Sian Gregory, Zoe Hewitt, Duncan Baker, Jason Halliwell, Harry Moore, Emanuele Ricci, Peter W Andrews, Harish Poptani, David C Hay, B Kevin Park, Chris E P Goldring

Systems analysis of miRNA biomarkers to inform drug safety

利用miRNA生物标志物进行系统分析以指导药物安全性

Schofield, Amy L; Brown, Joseph P; Brown, Jack; Wilczynska, Ania; Bell, Catherine; Glaab, Warren E; Hackl, Matthias; Howell, Lawrence; Lee, Stephen; Dear, James W; Remes, Mika; Reeves, Paul; Zhang, Eunice; Allmer, Jens; Norris, Alan; Falciani, Francesco; Takeshita, Louise Y; Seyed Forootan, Shiva; Sutton, Robert; Park, B Kevin; Goldring, Chris

Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification

小鼠胆源性肝类器官的蛋白质组学分析及其药物处置、生物活化和解毒能力

Lawrence Howell #, Rosalind E Jenkins #, Stephen Lynch #, Carrie Duckworth, B Kevin Park, Christopher Goldring

Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells

评估基于SWATH-MS的慢性淋巴细胞白血病细胞蛋白质组学分析中的技术和生物学变异

Eagle, Gina L; Herbert, John M J; Zhuang, Jianguo; Oates, Melanie; Khan, Umair T; Kitteringham, Neil R; Clarke, Kim; Park, B Kevin; Pettitt, Andrew R; Jenkins, Rosalind E; Falciani, Francesco

Deciphering Adverse Drug Reactions: In Vitro Priming and Characterization of Vancomycin-Specific T Cells From Healthy Donors Expressing HLA-A*32:01

解读药物不良反应:健康供体表达 HLA-A*32:01 的万古霉素特异性 T 细胞的体外启动和表征

Monday O Ogese, Adam Lister, Joshua Gardner, Xiaoli Meng, Ana Alfirevic, Munir Pirmohamed, B Kevin Park, Dean J Naisbitt

Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine

卡马西平群体药代动力学中临床和遗传因素的评估

Yip, Vincent L M; Pertinez, Henry; Meng, Xiaoli; Maggs, James L; Carr, Daniel F; Park, B Kevin; Marson, Anthony G; Pirmohamed, Munir

Retraction notice to "Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity": J Hepatol 56(2012)1070-1079

撤稿声明:“HMGB1 和角蛋白-18 的分子形式作为对乙酰氨基酚临床肝毒性中细胞死亡方式和预后的机制生物标志物”:J Hepatol 56(2012)1070-1079

Antoine, Daniel J; Jenkins, Rosalind E; Dear, James W; Williams, Dominic P; McGill, Mitchell R; Sharpe, Matthew R; Craig, Darren G; Simpson, Kenneth J; Jaeschke, Hartmut; Park, B Kevin

Alternatively activated macrophages promote resolution of necrosis following acute liver injury

替代性活化巨噬细胞促进急性肝损伤后坏死消退

Philip Starkey Lewis, Lara Campana, Niya Aleksieva, Jennifer Ann Cartwright, Alison Mackinnon, Eoghan O'Duibhir, Timothy Kendall, Matthieu Vermeren, Adrian Thomson, Victoria Gadd, Benjamin Dwyer, Rhona Aird, Tak-Yung Man, Adriano Giorgio Rossi, Lesley Forrester, B Kevin Park, Stuart John Forbes

Safety perspectives on presently considered drugs for the treatment of COVID-19

目前考虑用于治疗 COVID-19 的药物的安全性展望

Penman, Sophie L; Kiy, Robyn T; Jensen, Rebecca L; Beoku-Betts, Christopher; Alfirevic, Ana; Back, David; Khoo, Saye H; Owen, Andrew; Pirmohamed, Munir; Park, B Kevin; Meng, Xiaoli; Goldring, Christopher E; Chadwick, Amy E

Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity

关注事项:饮食限制抑制对乙酰氨基酚肝毒性期间的细胞凋亡和HMGB1氧化,并促进炎症细胞募集

Antoine, Daniel James; Williams, Dominic P; Kipar, Anja; Laverty, Hugh; Park, B Kevin