日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Towards catalytic fluoroquinolones: from metal-catalyzed to metal-free DNA cleavage

迈向催化型氟喹诺酮类药物:从金属催化到无金属催化DNA切割

Goldmeier, Moshe N; Khononov, Alina; Pieńko, Tomasz; Belakhov, Valery; Yen, Feng-Chun; Baruch, Limor; Machluf, Marcelle; Baasov, Timor

Dynamic Intramolecular Cap for Preserving Metallodrug Integrity─A Case of Catalytic Fluoroquinolones

动态分子内帽保护金属药物完整性─以催化氟喹诺酮类药物为例

Moshe N Goldmeier, Alina Khononov, Valery Belakhov, Tomasz Pieńko, Noam Orbach, Yuval Gilad Barzilay, Timor Baasov

Cross-utilization of β-galactosides and cellobiose in Geobacillus stearothermophilus

嗜热脂肪芽孢杆菌中β-半乳糖苷和纤维二糖的交叉利用

Smadar Shulami, Arie Zehavi, Valery Belakhov, Rachel Salama, Shifra Lansky, Timor Baasov, Gil Shoham, Yuval Shoham

Exploring eukaryotic versus prokaryotic ribosomal RNA recognition with aminoglycoside derivatives

利用氨基糖苷类衍生物探索真核生物与原核生物核糖体RNA的识别

Sabbavarapu, Narayana Murthy; Pieńko, Tomasz; Zalman, Bat-Hen; Trylska, Joanna; Baasov, Timor

New inducible genetic method reveals critical roles of GABA in the control of feeding and metabolism

一种新的诱导遗传方法揭示了GABA在摄食和代谢控制中的关键作用

Meng, Fantao; Han, Yong; Srisai, Dollada; Belakhov, Valery; Farias, Monica; Xu, Yong; Palmiter, Richard D; Baasov, Timor; Wu, Qi

A Hybrid Drug Limits Resistance by Evading the Action of the Multiple Antibiotic Resistance Pathway

一种混合药物通过规避多重抗生素耐药途径的作用来限制耐药性

Wang, Kathy K; Stone, Laura K; Lieberman, Tami D; Shavit, Michal; Baasov, Timor; Kishony, Roy

Structural basis for selective targeting of leishmanial ribosomes: aminoglycoside derivatives as promising therapeutics

利什曼原虫核糖体选择性靶向的结构基础:氨基糖苷类衍生物作为有前途的治疗方法

Moran Shalev, Haim Rozenberg, Boris Smolkin, Abedelmajeed Nasereddin, Dmitry Kopelyanskiy, Valery Belakhov, Thomas Schrepfer, Jochen Schacht, Charles L Jaffe, Noam Adir, Timor Baasov

Synthetic aminoglycosides efficiently suppress cystic fibrosis transmembrane conductance regulator nonsense mutations and are enhanced by ivacaftor

合成氨基糖苷类抗生素能有效抑制囊性纤维化跨膜传导调节因子无义突变,且其疗效可被伊伐卡托增强。

Xue, Xiaojiao; Mutyam, Venkateshwar; Tang, Liping; Biswas, Silpak; Du, Ming; Jackson, Laura A; Dai, Yanying; Belakhov, Valery; Shalev, Moran; Chen, Fuquan; Schacht, Jochen; J Bridges, Robert; Baasov, Timor; Hong, Jeong; Bedwell, David M; Rowe, Steven M

Long-term nonsense suppression therapy moderates MPS I-H disease progression

长期无义突变抑制疗法可延缓MPS IH疾病进展。

Gunn, Gwen; Dai, Yanying; Du, Ming; Belakhov, Valery; Kandasamy, Jeyakumar; Schoeb, Trenton R; Baasov, Timor; Bedwell, David M; Keeling, Kim M

Aminoglycoside-Induced Premature Stop Codon Read-Through of Mucopolysaccharidosis Type I Patient Q70X and W402X Mutations in Cultured Cells

氨基糖苷类药物诱导I型粘多糖贮积症患者Q70X和W402X突变在培养细胞中发生提前终止密码子通读

Kamei, Makoto; Kasperski, Karissa; Fuller, Maria; Parkinson-Lawrence, Emma J; Karageorgos, Litsa; Belakhov, Valery; Baasov, Timor; Hopwood, John J; Brooks, Doug A