日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Cyclic GMP-AMP synthase deficiency predisposes the liver to alcohol-induced cell death and ER stress

环磷酸鸟苷-AMP合成酶缺乏会使肝脏更容易受到酒精诱导的细胞死亡和内质网应激的影响。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000908
Babuta, Mrigya; Datta, Aditi Ashish; de Carvalho Ribeiro, Marcelle; Santos, Bruna de Araújo Cardoso Dos; Morel, Caroline; Copeland, Christopher; Ortega-Ribera, Marti; Mehta, Jeeval; Calenda, Charles; Wang, Yanbo; Remotti, Victoria; Brezani, Viliam; Patel, Arman; Hawryluk, Danielle; Szabo, Gyongyi
细胞生物学
内质网应激
发表日期：2026
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Transcriptome of monocytes from liver, brain and bone marrow reveals organ-specific features in aging and alcohol misuse

肝脏、大脑和骨髓单核细胞的转录组揭示了衰老和酒精滥用中的器官特异性特征

期刊:Jhep Reports
影响因子:9.5
doi:10.1016/j.jhepr.2025.101603
Martí Ortega-Ribera ，Radhika Joshi ，Sergi Guixé-Muntet ，Veronika Brezani ，Prashanth Thevkar Nagesh ，Viliam Brezani ，Arman Patel ，Yuan Zhuang ，Mrigya Babuta ，Jordi Gracia-Sancho ，Gyongyi Szabo
神经科学
发表日期：2025
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A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition

一种新型多器官雄性酒精性急性加慢性肝衰竭模型揭示了NET介导的肝细胞死亡，而RIPK3抑制剂可阻止这种死亡。

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2024.101446
Martí Ortega-Ribera ，Yuan Zhuang ，Mrigya Babuta ，Veronika Brezani ，Radhika S Joshi ，Zsuzsanna Zsengeller ，Prashanth Thevkar Nagesh ，Yanbo Wang ，Roderick Bronson ，Gyongyi Szabo
细胞生物学
RIPK3
肝衰竭
RIP
毒理研究
发表日期：2025
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The efficacy of rosuvastatin to reduce circulating tissue factor extracellular vesicles after ovarian cancer surgery

瑞舒伐他汀降低卵巢癌手术后循环组织因子细胞外囊泡的疗效

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2025016107
Osataphan, Soravis; Patell, Rushad; Babuta, Mrigya; Rosovsky, Rachel P; Hisada, Yohei; Edmiston, Charly; Elavalakanar, Pavania; Pfeffer, Michael A; Bregar, Amy; Ramos, Amanda; Garrett, Leslie; Ren, Siyang; Neuberg, Donna; Szabo, Gyongyi; Flaumenhaft, Robert; Mackman, Nigel; Shea, Meghan; Zwicker, Jeffrey I
肿瘤
肿瘤免疫
卵巢癌
囊泡
细胞生物学
发表日期：2025
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RAS/PI3K pathway mutations sensitise epithelial ovarian cancer cells to a PARP/NAMPT inhibitor combination.

RAS/PI3K通路突变使上皮性卵巢癌细胞对PARP/NAMPT抑制剂组合敏感。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-09223-0
Gruet Michael, Xu Yitao, An Lyutong, Ma Yurui, Balcells Cristina, Tyson Katie, Evangelista Laila C, Spear Sarah, Xu Yuewei, McKinney Flora, Babuta Julia, Bray Chandler, Wickremesinghe Chiharu, Siskos Alexandros P, Nijhuis Anke M, Tate Edward W, McNeish Iain A, Benito Adrian, Keun Hector C
卵巢癌
细胞生物学
RAS
PARP
NAMPT
PI3K/Akt
发表日期：2025
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Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis

中性粒细胞胞外陷阱通过NLRP3感应激活肝星状细胞和单核细胞，从而加速酒精诱导的MASH纤维化。

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2023-331447
Babuta, Mrigya; Morel, Caroline; de Carvalho Ribeiro, Marcelle; Calenda, Charles; Ortega-Ribera, Martí; Thevkar Nagesh, Prashanth; Copeland, Christopher; Zhuang, Yuan; Wang, Yanbo; Cho, Yeonhee; Joshi, Radhika; Brezani, Viliam; Hawryluk, Danielle; Datta, Aditi Ashish; Mehta, Jeeval; Nasser, Imad; Szabo, Gyongyi
中性粒细胞
粒细胞
LRP3
单核细胞
NLRP3
细胞生物学
发表日期：2024
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis

体内布鲁顿酪氨酸激酶抑制剂通过调节CD84介导的粒细胞生成来减轻酒精相关性肝病

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adg1915
Nagesh, Prashanth Thevkar; Cho, Yeonhee; Zhuang, Yuan; Babuta, Mrigya; Ortega-Ribera, Marti; Joshi, Radhika; Brezani, Veronika; Patel, Arman; Datta, Aditi Ashish; Brezani, Viliam; Hsieh, Yun-Cheng; Ramos, Adriana; Mehta, Jeeval; Copeland, Christopher; Kanata, Eleni; Jiang, Zhenghui Gordon; Vlachos, Ioannis; Asara, John; Szabo, Gyongyi
T细胞
信号转导
CD8
粒细胞
CD84
细胞生物学
发表日期：2024
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Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1β Axis in the Liver

MASH饮食和酒精暴饮的联合作用会通过肝脏中的NLRP3-IL-1β轴激活细胞间通讯和中性粒细胞募集

期刊:Cells
影响因子:5.1
doi:10.3390/cells13110960
Mrigya Babuta ，Prashanth Thevkar Nagesh ，Aditi Ashish Datta ，Victoria Remotti ，Yuan Zhuang ，Jeeval Mehta ，Francesca Lami ，Yanbo Wang ，Gyongyi Szabo
中性粒细胞
NLRP3
粒细胞
细胞生物学
LRP3
IL-1β
发表日期：2024
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A novel experimental model of MetALD in male mice recapitulates key features of severe alcohol-associated hepatitis

一种新型的雄性小鼠代谢性酒精性肝病（MetALD）实验模型重现了严重酒精相关性肝炎的关键特征。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000450
Babuta, Mrigya; Morel, Caroline; de Carvalho Ribeiro, Marcelle; Datta, Aditi Ashish; Calenda, Charles; Copeland, Christopher; Nasser, Imad; Szabo, Gyongyi
肝炎
代谢
发表日期：2024
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G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF

在酒精诱导的急性肝衰竭小鼠模型中，G-CSF 可增加钙卫蛋白表达、肝损伤和神经炎症。

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.6
doi:10.3389/fcell.2024.1347395
Martí Ortega-Ribera ，Yuan Zhuang ，Veronika Brezani ，Prashanth Thevkar Nagesh ，Radhika S Joshi ，Mrigya Babuta ，Yanbo Wang ，Gyongyi Szabo
肝衰竭
炎症/感染
G-CSF
肝损伤
毒理研究
神经科学
神经炎症
炎症
发表日期：2024
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