日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Versatile hiPSC Models and Bioengineering Platforms for Investigation of Atrial Fibrosis and Fibrillation

用于研究心房纤维化和颤动的多功能hiPSC模型和生物工程平台

Panahi, Behnam; Dababneh, Saif; Fadaei, Saba; Babini, Hosna; Singh, Sanjana; Prondzynski, Maksymilian; Akbari, Mohsen; Backx, Peter H; Andrade, Jason G; Rose, Robert A; Tibbits, Glen F

Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy.

脂联素受体激动剂可预防杜氏肌营养不良症小鼠模型的右心室组织病变

Gandhi Shivam, Delfinis Luca J, Bhatt Parashar D, Garibotti Madison C, Bellissimo Catherine A, Goli Amireza N, Morris Brooke A, Brahmbhatt Aditya N, Yakobov-Shimonov Simona, Rahman Fasih A, Quadrilatero Joe, Simpson Jeremy A, Sweeney Gary, Abdul-Sater Ali A, Backx Peter H, Hsu Henry H, Perry Christopher G R

Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20

杜氏肌营养不良症晚期线粒体兴奋效应揭示了一种氧化还原敏感的肌酸通路,该通路可被线粒体靶向肽SBT-20增强。

Hughes, Meghan C; Ramos, Sofhia V; Brahmbhatt, Aditya N; Turnbull, Patrick C; Polidovitch, Nazari N; Garibotti, Madison C; Schlattner, Uwe; Hawke, Thomas J; Simpson, Jeremy A; Backx, Peter H; Perry, Christopher Gr

Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3

对衰竭的人类左心室进行蛋白质组学和磷酸化蛋白质组学分析,发现扩张型心肌病相关的CTNNA3磷酸化

Reitz, Cristine J; Tavassoli, Marjan; Kim, Da Hye; Shah, Saumya; Lakin, Robert; Teng, Allen C T; Zhou, Yu-Qing; Li, Wenping; Hadipour-Lakmehsari, Sina; Backx, Peter H; Emili, Andrew; Oudit, Gavin Y; Kuzmanov, Uros; Gramolini, Anthony O

Dissecting the Roles of the Autonomic Nervous System and Physical Activity on Circadian Heart Rate Fluctuations in Mice

剖析自主神经系统和身体活动对小鼠昼夜心率波动的影响

Barazi, Nour; Polidovitch, Nazari; Debi, Ryan; Yakobov, Simona; Lakin, Robert; Backx, Peter H

Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation

阿佩林可提高心房传导速度和不应期,并抑制心房颤动的诱发。

Kim, Young M; Lakin, Robert; Zhang, Hao; Liu, Jack; Sachedina, Ayaaz; Singh, Maneesh; Wilson, Emily; Perez, Marco; Verma, Subodh; Quertermous, Thomas; Olgin, Jeffrey; Backx, Peter H; Ashley, Euan A

Revisiting right anterior oblique projections for the triangle of Koch: implications from computed tomography

重新审视右前斜位投照在科赫三角中的应用:来自计算机断层扫描的启示

Wang, Yanjing; Liu, Lin; Lakin, Robert; Polidovitch, Nazari; Liu, Guohui; Yang, Hongliang; Yu, Ming; Yan, Mingzhou; Zhao, Dong; Backx, Peter H; Sun, Huan; He, Yuquan; Yang, Ping

CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage

CFTR疗法可使小鼠心力衰竭和蛛网膜下腔出血模型中的脑灌注不足恢复正常

Lidington, Darcy; Fares, Jessica C; Uhl, Franziska E; Dinh, Danny D; Kroetsch, Jeffrey T; Sauvé, Meghan; Malik, Firhan A; Matthes, Frank; Vanherle, Lotte; Adel, Arman; Momen, Abdul; Zhang, Hangjun; Aschar-Sobbi, Roozbeh; Foltz, Warren D; Wan, Hoyee; Sumiyoshi, Manabu; Macdonald, R Loch; Husain, Mansoor; Backx, Peter H; Heximer, Scott P; Meissner, Anja; Bolz, Steffen-Sebastian

Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na+ channel blocking pharmacotherapy for de novo conduction disease

一种与长QT间期和布鲁加达综合征相关的新型SCN5A复合突变中的复杂相互作用:对新发传导疾病的钠通道阻滞药物治疗的启示

Liu, Jie; Bayer, Jason D; Aschar-Sobbi, Roozbeh; Wauchop, Marianne; Spears, Danna; Gollob, Michael; Vigmond, Edward J; Tsushima, Robert; Backx, Peter H; Chauhan, Vijay S

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

环状RNA结合并激活AKT,使其磷酸化并定位至细胞核,从而减少细胞凋亡并促进心脏修复。

Zeng, Yan; Du, William W; Wu, Yingya; Yang, Zhenguo; Awan, Faryal Mehwish; Li, Xiangmin; Yang, Weining; Zhang, Chao; Yang, Qi; Yee, Albert; Chen, Yu; Yang, Fenghua; Sun, Huan; Huang, Ren; Yee, Albert J; Li, Ren-Ke; Wu, Zhongkai; Backx, Peter H; Yang, Burton B