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日期影响因子

TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration

TBK1诱导Optineurin丝状体的形成，该丝状体与多聚泛素和LC3凝聚，从而隔离货物。

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202509927

Herrera, Maria G; Kühn, Lena; Jungbluth, Lisa; Bader, Verian; Krause, Laura J; Kartte, David; Adriaenssens, Elias; Martens, Sascha; Tatzelt, Jörg; Sachse, Carsten; Winklhofer, Konstanze F

发表日期：2026

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A Novel 3D Semi-Automated Full Quantification Technique for Detection of Intraneural Phospho-α-Synuclein in Skin Biopsies

一种用于检测皮肤活检组织中神经元内磷酸化α-突触核蛋白的新型3D半自动全定量技术

期刊:European Journal of Neurology

影响因子:3.9

doi:10.1111/ene.70525

Lonczewski, Sophia; Bader, Verian; Ortmann, Louisa; Basner, Louisa; Stücker, Markus; Gold, Ralf; Scherbaum, Raphael; Kwon, Eun Hae; Winklhofer, Konstanze F; Tönges, Lars

发表日期：2026

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Phosphoinositide kinase PIKfyve inhibitor apilimod blocks hepatitis E virus infection

磷脂酰肌醇激酶 PIKfyve 抑制剂 apilimod 可阻断戊型肝炎病毒感染

doi:10.1136/egastro-2025-100348

Ring, Julian J; Schlienkamp, Sarah; Goussain Darido, Maria L; Zhang, Xin; Pinto Veiga, Olinda; Haase, Jil Alexandra; Richter, Emely; Gömer, André; Fu, Rebecca Menhua; Dao Thi, Viet Loan; Ulrich, Rainer G; Klöhn, Mara; Todt, Daniel; Bader, Verian; Winklhofer, Konstanze F; Kinast, Volker; Neyts, Johan; Kaptein, Suzanne J F; Steinmann, Eike; Brüggemann, Yannick

发表日期：2026

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Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival.

受损溶酶体上的线性泛素化诱导局部 NFKB 激活并控制细胞存活

期刊:Autophagy

影响因子:14.3

doi:10.1080/15548627.2024.2443945

Zein Laura, Dietrich Marvin, Balta Denise, Bader Verian, Scheuer Christoph, Zellner Suzanne, Weinelt Nadine, Vandrey Julia, Mari Muriel C, Behrends Christian, Zunke Friederike, Winklhofer Konstanze F, Van Wijk Sjoerd J L

细胞生物学

发表日期：2025

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Topological confinement by a membrane anchor suppresses phase separation into protein aggregates: Implications for prion diseases

膜锚定的拓扑约束抑制蛋白质聚集体的相分离：对朊病毒疾病的启示

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2415250121

Gogte, Kalpshree; Mamashli, Fatemeh; Herrera, Maria Georgina; Kriegler, Simon; Bader, Verian; Kamps, Janine; Grover, Prerna; Winter, Roland; Winklhofer, Konstanze F; Tatzelt, Jörg

发表日期：2025

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The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

P2X7R拮抗剂AFC-5128在预防和治疗模式下可改善慢性实验性自身免疫性脑脊髓炎

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1554999

Hoffrogge, Robert; Karachunskaya, Anna; Heitmann, Neele; Haupeltshofer, Steffen; Pedreiturria, Xiomara; Klöster, Katharina; Bader, Verian; Winklhofer, Konstanze F; Hamacher, Michael; Klebl, Bert; Gold, Ralf; Dinkel, Klaus; Kleiter, Ingo; Faissner, Simon

免疫/内分泌

发表日期：2025

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Correction: The P2X7R-antagonist AFC-5128 ameliorates chronic experimental autoimmune encephalomyelitis in a preventive and therapeutic paradigm

更正：P2X7R拮抗剂AFC-5128在预防和治疗模式下可改善慢性实验性自身免疫性脑脊髓炎

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1652299

Hoffrogge, Robert; Karachunskaya, Anna; Heitmann, Neele; Haupeltshofer, Steffen; Pedreiturria, Xiomara; Klöster, Katharina; Bader, Verian; Winklhofer, Konstanze F; Hamacher, Michael; Klebl, Bert; Gold, Ralf; Dinkel, Klaus; Kleiter, Ingo; Faissner, Simon

免疫/内分泌

发表日期：2025

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Loss of Atoh8 Impairs Macroautophagy.

Atoh8 的缺失会损害巨自噬。

影响因子:5.2

doi:10.3390/cells14241993

Divvela Satya Srirama Karthik, Offei Eric Bekoe, Kadr Hawi, Hausherr Maximilian, Eggers Britta, Rozanova Svitlana, Eisenacher Martin, Nguyen Hoang Duy, Tuoc Tran, Bader Verian, Yang Xuesong, Zaehres Holm, Chen Anqi, Nguyen Huu Phuc, Winklhofer Konstanze F, Marcus Katrin, Brand-Saberi Beate

发表日期：2025

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Combined loss of brevican, neurocan, tenascin-C and tenascin-R leads to impaired fear retrieval due to perineuronal net loss

brevican、neurocan、tenascin-C 和 tenascin-R 的联合缺失会导致神经元周围净损失，从而损害恐惧提取能力。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-89580-2

Mueller-Buehl, Cornelius; Pakusch, Johanna; Bader, Verian; Winklhofer, Konstanze F; Mark, Melanie D; Faissner, Andreas

发表日期：2025

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Liquid-liquid phase separation of the prion protein is regulated by the octarepeat domain independently of histidines and copper

朊病毒蛋白的液-液相分离受八肽重复结构域调控，且该调控独立于组氨酸和铜。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2024.107310

Kamps, Janine; Bader, Verian; Winklhofer, Konstanze F; Tatzelt, Jörg

发表日期：2024

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