Bading Hilmar相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The NMDAR/TRPM4 death complex is a major promoter of disease progression in the 5xFAD mouse model of Alzheimer's disease.

NMDAR/TRPM4死亡复合物是阿尔茨海默病5xFAD小鼠模型中疾病进展的主要促进因素。

期刊:Molecular Psychiatry

影响因子:10.1

doi:10.1038/s41380-025-03143-5

Yan Jing, Yang Xiaohui, Li Guilin, Ramirez Omar A, Hagenston Anna M, Chen Zhe-Yu, Bading Hilmar

阿尔茨海默症

发表日期：2026

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Pharmacological Targeting of the NMDAR/TRPM4 Death Signaling Complex with a TwinF Interface Inhibitor Prevents Excitotoxicity-Associated Dendritic Blebbing and Organelle Damage.

利用 TwinF 界面抑制剂对 NMDAR/TRPM4 死亡信号复合物进行药理学靶向，可防止兴奋性毒性相关的树突起泡和细胞器损伤

影响因子:5.2

doi:10.3390/cells14030195

RamÃrez Omar A, Hellwig Andrea, Zhang Zihong, Bading Hilmar

细胞生物学

发表日期：2025

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Inhba, Homer1 and Bdnf are major targets of transcriptomic dysregulation by neurodegenerative disease-associated excitotoxic NMDA receptor signaling.

Inhba、Homer1 和 Bdnf 是神经退行性疾病相关的兴奋性毒性 NMDA 受体信号传导导致转录组失调的主要靶点。

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-09074-9

OberlÃ¤nder Kristin, Pruunsild Priit, Koch Philipp, Yan Jing, Szafranski Karol, Bading Hilmar

发表日期：2025

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The Disruption of NMDAR/TRPM4 Death Signaling with TwinF Interface Inhibitors: A New Pharmacological Principle for Neuroprotection

TwinF界面抑制剂干扰NMDAR/TRPM4死亡信号通路：一种新的神经保护药理学原理

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph16081085

Yan, Jing; Bading, Hilmar

发表日期：2023

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Dysregulation of Npas4 and Inhba expression and an altered excitation-inhibition balance are associated with cognitive deficits in DBA/2 mice

Npas4和Inhba表达失调以及兴奋-抑制平衡改变与DBA/2小鼠的认知缺陷有关。

期刊:Learning & Memory

影响因子:2.2

doi:10.1101/lm.053527.121

Oberländer, Kristin; Witte, Victoria; Mallien, Anne Stephanie; Gass, Peter; Bengtson, C Peter; Bading, Hilmar

发表日期：2022

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The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health

核内钙离子在维持神经元稳态和脑健康中的作用

期刊:Journal of Cell Science

影响因子:3.6

doi:10.1242/jcs.254904

Mozolewski, Pawel; Jeziorek, Maciej; Schuster, Christoph M; Bading, Hilmar; Frost, Bess; Dobrowolski, Radek

发表日期：2021

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Functional Consequences of Calcium-Dependent Synapse-to-Nucleus Communication: Focus on Transcription-Dependent Metabolic Plasticity

钙依赖性突触-细胞核通讯的功能后果：聚焦转录依赖性代谢可塑性

期刊:Cold Spring Harbor Perspectives in Biology

影响因子:8.4

doi:10.1101/cshperspect.a035287

Hagenston, Anna M; Bading, Hilmar; Bas-Orth, Carlos

细胞生物学

发表日期：2020

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A microscopy-based small molecule screen in primary neurons reveals neuroprotective properties of the FDA-approved anti-viral drug Elvitegravir

一项基于显微镜的小分子筛选研究在原代神经元中揭示了FDA批准的抗病毒药物埃尔维特格拉韦的神经保护特性。

期刊:Molecular Brain

影响因子:2.9

doi:10.1186/s13041-020-00641-1

Merz, Simon F; Bengtson, C Peter; Tepohl, Clara; Hagenston, Anna M; Bading, Hilmar; Bas-Orth, Carlos

发表日期：2020

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Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2

表观遗传学通过新生DNA甲基转移酶Dnmt3a2调控慢性炎症性疼痛中的过敏反应

期刊:Molecular Pain

影响因子:2.8

doi:10.1177/1744806919827469

Oliveira, Ana Mm; Litke, Christian; Paldy, Eszter; Hagenston, Anna M; Lu, Jianning; Kuner, Rohini; Bading, Hilmar; Mauceri, Daniela

发表日期：2019

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Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations

针对神经退行性疾病中突触外NMDA受体信号传导病理三联体的治疗靶向

期刊:Journal of Experimental Medicine

影响因子:10.6

doi:10.1084/jem.20161673

发表日期：2017

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