日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis.

小分子 MST1/2 抑制剂可加速小鼠肝脏再生，提高脂肪性肝炎模型小鼠的存活率

期刊:PNAS Nexus
影响因子:3.8
doi:10.1093/pnasnexus/pgae096
Watkins Ryan, Gamo Ana, Choi Seung Hyuk, Kumar Manoj, Buckarma EeeLN, McCabe Chantal, Tomlinson Jennifer, Pereya David, Lupse Blaz, Geravandi Shirin, Werneburg Nathan W, Wang Chen, Starlinger Patrick, Zhu Siying, Li Sijia, Yu Shan, Surakattula Murali, Baguley Tyler, Ardestani Amin, Maedler Kathrin, Roland Jason, Nguyen-Tran Van, Joseph Sean, Petrassi Mike, Rogers Nikki, Gores Gregory, Chatterjee Arnab, Tremblay Matthew, Shen Weijun, Smoot Rory
免疫/内分泌
发表日期：2024
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Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

谷胱甘肽响应性硒硫化物前药作为平台策略，用于高效、选择性地基于机制抑制蛋白酪氨酸磷酸酶

期刊:ACS Central Science
影响因子:10.4
doi:10.1021/acscentsci.7b00486
Tjin, Caroline Chandra; Otley, Kate D; Baguley, Tyler D; Kurup, Pradeep; Xu, Jian; Nairn, Angus C; Lombroso, Paul J; Ellman, Jonathan A
发表日期：2017
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Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels

在细胞和动物模型中，BDNF表达下调会增加纹状体富集蛋白酪氨酸磷酸酶61 (STEP61) 的水平。

期刊:Journal of Neurochemistry
影响因子:4
doi:10.1111/jnc.13295
Xu, Jian; Kurup, Pradeep; Azkona, Garikoitz; Baguley, Tyler D; Saavedra, Ana; Nairn, Angus C; Ellman, Jonathan A; Pérez-Navarro, Esther; Lombroso, Paul J
BDNF
细胞生物学
发表日期：2016
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Synthesis of benzopentathiepin analogs and their evaluation as inhibitors of the phosphatase STEP

苯并五硫杂环庚烯类似物的合成及其作为STEP磷酸酶抑制剂的评价

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2015.01.020
Baguley, Tyler D; Nairn, Angus C; Lombroso, Paul J; Ellman, Jonathan A
发表日期：2015
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Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

基于片段的结核分枝杆菌蛋白酪氨酸磷酸酶 PtpA 选择性抑制剂的发现

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2009.10.090
Rawls, Katherine A; Lang, P Therese; Takeuchi, Jun; Imamura, Shinichi; Baguley, Tyler D; Grundner, Christoph; Alber, Tom; Ellman, Jonathan A
发表日期：2009
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