日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Phase I Trial to Determine the Safety and Tolerability of Autophagy Inhibition Using Chloroquine or Hydroxychloroquine in Combination with Carboplatin and Gemcitabine in Patients with Advanced Solid Tumorsced solid tumors

一项I期临床试验旨在确定在晚期实体瘤患者中,使用氯喹或羟氯喹联合卡铂和吉西他滨抑制自噬的安全性和耐受性。

Abdel Karim, Nagla; Eldessouki, Ihab; Ahmed, Imran; Gaber, Ola; Bahassi, Elmustapha; Khaled, Ahmed; Davis, Harlod; Morris, John C

Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer

Nardilysin 调节的断裂机制激活 polo 样激酶 3 以抑制胰腺癌的发展

Jie Fu #, Jianhua Ling #, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, Junwei Hou, Ping Chen, Yu Cao, Ya'an Kang, Yichen Sun, Xianghou Xia, Zhou Jiang, Kenei Furukawa, Yu Lu, Min Wu, Qian Huang, Jun Yao, David H Hawke, Bih-Fang Pan, Jun Zhao, Jiaxing Huang, Huamin Wang, E I Mustapha Bahassi, Peter J Sta

A Phase I Trial to Determine the Safety and Tolerability of Autophagy Inhibition Using Chloroquine or Hydroxychloroquine in Combination With Carboplatin and Gemcitabine in Patients With Advanced Solid Tumors

一项 I 期临床试验旨在确定使用氯喹或羟氯喹联合卡铂和吉西他滨对晚期实体瘤患者进行自噬抑制的安全性和耐受性

Nagla Abdel Karim, Asad Ullah, Imran Ahmad, Elmustapha Bahassi, Olugbenga Olowokure, Ahmed Khaled, Harold Davis, John C Morris

Patient-Derived Organotypic Epithelial Rafts Model Phenotypes in Juvenile-Onset Recurrent Respiratory Papillomatosis

患者来源的器官型上皮筏模型青少年复发性呼吸道乳头状瘤病的表型

Mary C Bedard, Marion G Brusadelli, Adrean Carlile, Sonya Ruiz-Torres, Hannah Lodin, Denis Lee, Matthew Kofron, Paul F Lambert, Adam Lane, Najim Ameziane, El Mustapha Bahassi, Kathryn A Wikenheiser-Brokamp, Alessandro de Alarcon, David F Smith, Susanne I Wells

Exosomes as a Surrogate Marker for Autophagy in Peripheral Blood, Correlative Data from Phase I Study of Chloroquine in Combination with Carboplatin/Gemcitabine in Advanced Solid Tumors

外泌体作为外周血自噬的替代标记,氯喹联合卡铂/吉西他滨治疗晚期实体瘤的 I 期研究的相关数据

Nagla Abdel Karim, Ola Gaber, Hashim M Aljohani, Ihab Eldessouki, El Mustapha Bahassi, John Morris

Genetic mutations associated with lung cancer metastasis to the brain

与肺癌脑转移相关的基因突变

Hashim M Aljohani, Mohamed Aittaleb, John M Furgason, Peter Amaya, Ayham Deeb, Jeffery J Chalmers, El Mustapha Bahassi

PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas

PLK1 抑制可增强替莫唑胺对 IDH1 突变型胶质瘤的疗效

Robert F Koncar, Zhengtao Chu, Lindsey E Romick-Rosendale, Susanne I Wells, Timothy A Chan, Xiaoyang Qi, El Mustapha Bahassi

Brain Tumor Epidemiology - A Hub within Multidisciplinary Neuro-oncology. Report on the 15th Brain Tumor Epidemiology Consortium (BTEC) Annual Meeting, Vienna, 2014

脑肿瘤流行病学——多学科神经肿瘤学中心。第十五届脑肿瘤流行病学联盟(BTEC)年会报告,维也纳,2014年

Woehrer, Adelheid; Lau, Ching C; Prayer, Daniela; Bauchet, Luc; Rosenfeld, Myrna; Capper, David; Fisher, Paul G; Kool, Marcel; Müller, Martin; Kros, Johan M; Kruchko, Carol; Wiemels, Joseph; Wrensch, Margaret; Danysh, Heather E; Zouaoui, Sonia; Heck, Julia E; Johnson, Kimberly J; Qi, Xiaoyang; O'Neill, Brian P; Afzal, Samina; Scheurer, Michael E; Bainbridge, Matthew N; Nousome, Darryl; Bahassi, El Mustapha; Hainfellner, Johannes A; Barnholtz-Sloan, Jill S

ROS1 amplification mediates resistance to gefitinib in glioblastoma cells

ROS1 扩增介导胶质母细胞瘤细胞对吉非替尼的耐药性

Hashim Aljohani, Robert F Koncar, Ahmad Zarzour, Byung Sun Park, So Ha Lee, El Mustapha Bahassi

Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activation

多形性胶质母细胞瘤的全基因组测序发现了参与 EGFR 激活的多种结构变异。

John M Furgason ,Wenge Li ,Brandon Milholland ,Emily Cross ,Yaqin Li ,Christopher M McPherson ,Ronald E Warnick ,Olivier Rixe ,Peter J Stambrook ,Jan Vijg ,El Mustapha Bahassi