日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MK-8527 is a novel inhibitor of HIV-1 reverse transcriptase translocation with potential for extended-duration dosing

MK-8527 是一种新型的 HIV-1 逆转录酶易位抑制剂,具有延长给药时间的潜力。

Raheem, Izzat T; Girijavallabhan, Vinay; Fillgrove, Kerry L; Goh, Shih Lin; Bahnck-Teets, Carolyn; Huang, Qian; Li, Fangbiao; Wan, Bang-Lin; O'Donnell, Gregory T; Patteson, Jonathan B; Cilento, Maria E; Bennet, Amrith; Hayes, Robert P; Tummala, Srivanya; McHale, Carolyn; Wiltsie, Judyann; Ellis, Joan; Asante-Appiah, Ernest; Hazuda, Daria J; Hale, Jeffrey; Grobler, Jay A; Xu, Min; Diamond, Tracy L; Lai, Ming-Tain

Novel Pan-Coronavirus 3CL Protease Inhibitor MK-7845: Biological and Pharmacological Profiling

新型泛冠状病毒 3CL 蛋白酶抑制剂 MK-7845:生物学和药理学分析

Nadine Alvarez, Gregory C Adam, John A Howe, Vijeta Sharma, Matthew D Zimmerman, Enriko Dolgov, Risha Rasheed, Fatima Nizar, Khushboo Sahay, Andrew M Nelson, Steven Park, Xiaoyan Zhou, Christine Burlein, John F Fay, Daniel V Iwamoto, Carolyn M Bahnck-Teets, Krista L Getty, Shih Lin Goh, Imad Salhab,

Intact Human Immunodeficiency Virus (HIV) Reservoir Estimated by the Intact Proviral DNA Assay Correlates With Levels of Total and Integrated DNA in the Blood During Suppressive Antiretroviral Therapy

通过完整前病毒 DNA 检测估计的完整人类免疫缺陷病毒 (HIV) 库与抑制性抗逆转录病毒治疗期间血液中的总 DNA 和整合 DNA 水平相关

Emmanouil Papasavvas, Livio Azzoni, Brian N Ross, Matthew Fair, Zhe Yuan, Kwasi Gyampoh, Agnieszka Mackiewicz, Amanda C Sciorillo, Amelie Pagliuzza, Steven M Lada, Guoxin Wu, Shih Lin Goh, Carolyn Bahnck-Teets, Daniel J Holder, Paul D Zuck, Mohammad Damra, Kenneth M Lynn, Pablo Tebas, Karam Mounzer,

Chondroitin sulfate promotes activation of cathepsin K

硫酸软骨素促进组织蛋白酶K的活化

Lemaire, Peter A; Huang, Lingyi; Zhuo, Ya; Lu, Jun; Bahnck, Carolyn; Stachel, Shawn J; Carroll, Steve S; Duong, Le T