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Discovery of highly potent naphthalene/quinoline-based PAD inhibitors: Structure-activity relationship, selectivity, and cytotoxicity

高效萘/喹啉类PAD抑制剂的发现：构效关系、选择性和细胞毒性

期刊:European Journal of Medicinal Chemistry

doi:10.1016/j.ejmech.2025.117830

Jia, Yijiang; Bahraminejad, Sina; Duan, Xin; Kong, Sydney; Taledaohan, Ayijiang; Jiang, Chenyao; Ma, Dejian; Jiang, Jianxiong; Wang, Yuji; Liu, Jiawang

Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive

舌下和颊部给药：历史和科学规范

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics17081073

Bahraminejad, Sina; Almoazen, Hassan

发表日期：2025

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New structural scaffolds to enhance the metabolic stability of arginine-derived PAD4 inhibitors

新型结构支架增强精氨酸衍生的PAD4抑制剂的代谢稳定性

期刊:Results in Chemistry

影响因子:4.2

doi:10.1016/j.rechem.2025.102162

Jia, Yijiang; Bahraminejad, Sina; Jiang, Chenyao; Taledaohan, Ayijiang; Ma, Dejian; Jiang, Jianxiong; Wang, Yuji; Liu, Jiawang

代谢

发表日期：2025

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Comparison of cytotoxicity of Miltefosine and its niosomal form on chick embryo model

米替福新及其脂质体形式对鸡胚模型细胞毒性的比较

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-024-52620-4

Seyedi, Fatemeh; Sharifi, Iraj; Khosravi, Ahmad; Molaakbari, Elaheh; Tavakkoli, Hadi; Salarkia, Ehsan; Bahraminejad, Sina; Bamorovat, Mehdi; Dabiri, Shahriar; Salari, Zohreh; Kamali, Ali; Ren, Guogang

Suppressing the Inflammatory Prostaglandin Signaling after Thrombotic Stroke Ameliorates Ischemic Brain Injury and Facilitates Poststroke Recovery.

抑制血栓性中风后的炎症性前列腺素信号传导可改善缺血性脑损伤并促进中风后恢复

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.4c00516

Jin Zhen, Jiang Chenyao, Cho Eun Bee, Bahraminejad Sina, Han Juqian, Hao Jiukuan, Liu Jiawang, Yu Ying, Jiang Jianxiong

Development of highly potent EP2 antagonists as novel anti-inflammatory neuroprotectants

开发高效EP2拮抗剂作为新型抗炎神经保护剂

Discovery of highly potent naphthalene/quinoline-based PAD inhibitors: Structure-activity relationship, selectivity, and cytotoxicity

高效萘/喹啉类PAD抑制剂的发现：构效关系、选择性和细胞毒性

Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive

舌下和颊部给药：历史和科学规范

New structural scaffolds to enhance the metabolic stability of arginine-derived PAD4 inhibitors

新型结构支架增强精氨酸衍生的PAD4抑制剂的代谢稳定性

Comparison of cytotoxicity of Miltefosine and its niosomal form on chick embryo model

米替福新及其脂质体形式对鸡胚模型细胞毒性的比较

Suppressing the Inflammatory Prostaglandin Signaling after Thrombotic Stroke Ameliorates Ischemic Brain Injury and Facilitates Poststroke Recovery.

抑制血栓性中风后的炎症性前列腺素信号传导可改善缺血性脑损伤并促进中风后恢复