日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection

重组微生物糖苷水解酶作为抗生物膜剂治疗急性肺部铜绿假单胞菌感染的临床前评价

Ostapska, Hanna; Raju, Deepa; Corsini, Rachel; Lehoux, Melanie; Lacdao, Ira; Gilbert, Stephanie; Sivarajah, Piyanka; Bamford, Natalie C; Baker, Perrin; Gravelat, Fabrice N; Howell, P Lynne; Sheppard, Donald C

Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases in the Prevention of Experimental Invasive Aspergillosis

重组微生物糖苷水解酶在预防实验性侵袭性曲霉病中的临床前评价

Ostapska, Hanna; Raju, Deepa; Lehoux, Melanie; Lacdao, Ira; Gilbert, Stephanie; Sivarajah, Piyanka; Bamford, Natalie C; Baker, Perrin; Nguyen, Thi Tuyet Mai; Zacharias, Caitlin A; Gravelat, Fabrice N; Howell, P Lynne; Sheppard, Donald C

Treatment with the Pseudomonas aeruginosa Glycoside Hydrolase PslG Combats Wound Infection by Improving Antibiotic Efficacy and Host Innate Immune Activity

利用铜绿假单胞菌糖苷水解酶 PslG 治疗可通过提高抗生素疗效和增强宿主先天免疫活性来对抗伤口感染

Pestrak, Matthew J; Baker, Perrin; Dellos-Nolan, Sheri; Hill, Preston J; Passos da Silva, Daniel; Silver, Holly; Lacdao, Ira; Raju, Deepa; Parsek, Matthew R; Wozniak, Daniel J; Howell, P Lynne

PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms

PgaB 直系同源物含有糖苷水解酶结构域,可裂解脱乙酰化的聚β(1,6)-N-乙酰氨基葡萄糖,并能破坏细菌生物膜。

Little, Dustin J; Pfoh, Roland; Le Mauff, François; Bamford, Natalie C; Notte, Christina; Baker, Perrin; Guragain, Manita; Robinson, Howard; Pier, Gerald B; Nitz, Mark; Deora, Rajendar; Sheppard, Donald C; Howell, P Lynne

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.

微生物糖苷水解酶作为具有跨界活性的抗生物膜剂

Snarr Brendan D, Baker Perrin, Bamford Natalie C, Sato Yukiko, Liu Hong, Lehoux Mélanie, Gravelat Fabrice N, Ostapska Hanna, Baistrocchi Shane R, Cerone Robert P, Filler Elan E, Parsek Matthew R, Filler Scott G, Howell P Lynne, Sheppard Donald C

Structural and functional characterization of Pseudomonas aeruginosa AlgX: role of AlgX in alginate acetylation

铜绿假单胞菌AlgX的结构和功能表征:AlgX在藻酸盐乙酰化中的作用

Riley, Laura M; Weadge, Joel T; Baker, Perrin; Robinson, Howard; Codée, Jeroen D C; Tipton, Peter A; Ohman, Dennis E; Howell, P Lynne

Rational approaches for engineering novel functionalities in carbon-carbon bond forming enzymes

构建碳碳键形成酶新功能的合理方法

Baker, Perrin; Seah, Stephen Y K