Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation.
Sirtuin-1 直接结合并使肝脏 PCSK9 去乙酰化，从而促进抑制 LDL 受体降解
期刊:Cardiovascular Research
影响因子:13.3
doi:10.1093/cvr/cvaf087
Velagapudi Srividya, Miranda Melroy X, Adla Priyanka, Kraler Simon, Mohammed Shafeeq A, Baki Shekhar, Robert Jerome, Rohrer Lucia, Lee Hwan, Jang Hyun-Duk, Obeid Slayman, Tailleux Anne, Staels Bart, Sepuri Naresh Babu V, Paneni Francesco, Gutti Ravi Kumar, von Eckardstein Arnold, Kim Hyo-Soo, Akhmedov Alexander, Camici Giovanni G, Lüscher Thomas F
