Genetic variation in GNB5 causes bradycardia by augmenting the cholinergic response via increased acetylcholine-activated potassium current (I(K,ACh)).
GNB5 的基因变异通过增加乙酰胆碱激活的钾电流 (I(K,ACh)) 来增强胆碱能反应，从而导致心动过缓
期刊:Disease Models & Mechanisms
影响因子:3.3
doi:10.1242/dmm.037994
Veerman Christiaan C, Mengarelli Isabella, Koopman Charlotte D, Wilders Ronald, van Amersfoorth Shirley C, Bakker Diane, Wolswinkel Rianne, Hababa Mariam, de Boer Teun P, Guan Kaomei, Milnes James, Lodder Elisabeth M, Bakkers Jeroen, Verkerk Arie O, Bezzina Connie R
