日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Imidazoquinoline Toll-Like Receptor-7/8 Agonist Hybrid-2 Potently Induces Cytokine Production by Human Newborn and Adult Leukocytes

咪唑喹啉类 Toll 样受体 7/8 激动剂杂合体 2 可有效诱导人类新生儿和成人白细胞产生细胞因子

Ganapathi, Lakshmi; Van Haren, Simon; Dowling, David J; Bergelson, Ilana; Shukla, Nikunj M; Malladi, Subbalakshmi S; Balakrishna, Rajalakshmi; Tanji, Hiromi; Ohto, Umeharu; Shimizu, Toshiyuki; David, Sunil A; Levy, Ofer

Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds.

人类 Toll 样受体 7 和 8 的活性决定因素:多种杂环骨架的定量构效关系 (QSAR)

Yoo Euna, Salunke Deepak B, Sil Diptesh, Guo Xiaoqiang, Salyer Alex C D, Hermanson Alec R, Kumar Manoj, Malladi Subbalakshmi S, Balakrishna Rajalakshmi, Thompson Ward H, Tanji Hiromi, Ohto Umeharu, Shimizu Toshiyuki, David Sunil A

Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines.

C2、C4 和 C8 修饰的噻唑并[4,5-c]喹啉类化合物的 Toll 样受体-8 激动活性

Kokatla Hari Prasad, Yoo Euna, Salunke Deepak B, Sil Diptesh, Ng Cameron F, Balakrishna Rajalakshmi, Malladi Subbalakshmi S, Fox Lauren M, David Sunil A

Toward self-adjuvanting subunit vaccines: model peptide and protein antigens incorporating covalently bound toll-like receptor-7 agonistic imidazoquinolines

构建自佐剂亚单位疫苗:模型肽和蛋白质抗原包含共价结合的 Toll 样受体 7 激动剂咪唑喹啉

Shukla, Nikunj M; Lewis, Tyler C; Day, Timothy P; Mutz, Cole A; Ukani, Rehman; Hamilton, Chase D; Balakrishna, Rajalakshmi; David, Sunil A

Comparison of the immunostimulatory and proinflammatory activities of candidate Gram-positive endotoxins, lipoteichoic acid, peptidoglycan, and lipopeptides, in murine and human cells

比较候选革兰氏阳性内毒素、脂磷壁酸、肽聚糖和脂肽在小鼠和人细胞中的免疫刺激和促炎活性

Kimbrell, Matthew R; Warshakoon, Hemamali; Cromer, Jens R; Malladi, Subbalakshmi; Hood, Jennifer D; Balakrishna, Rajalakshmi; Scholdberg, Tandace A; David, Sunil A

Protection from endotoxic shock by EVK-203, a novel alkylpolyamine sequestrant of lipopolysaccharide

EVK-203是一种新型烷基多胺脂多糖螯合剂,可保护机体免受内毒素休克的侵害。

Nguyen, Thuan B; Adisechan, Ashok Kumar; Suresh Kumar, E V K; Balakrishna, Rajalakshmi; Kimbrell, Matthew R; Miller, Kelly A; Datta, Apurba; David, Sunil A

Structural correlation between lipophilicity and lipopolysaccharide-sequestering activity in spermine-sulfonamide analogs

亚精胺磺酰胺类似物中亲脂性和脂多糖螯合活性之间的结构相关性

Burns, Mark R; Jenkins, Scott A; Vermeulen, Nicolas M; Balakrishna, Rajalakshmi; Nguyen, Thuan B; Kimbrell, Matthew R; David, Sunil A