日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P1 Receptor Modulator in Clinical Trials

BMS-986104的鉴定和临床前药理学研究:一种在临床试验中应用的差异化S1P1受体调节剂

Dhar, T G Murali; Xiao, Hai-Yun; Xie, Jenny; Lehman-McKeeman, Lois D; Wu, Dauh-Rurng; Dabros, Marta; Yang, Xiaoxia; Taylor, Tracy L; Zhou, Xia D; Heimrich, Elizabeth M; Thomas, Rochelle; McIntyre, Kim W; Warrack, Bethanne; Shi, Hong; Levesque, Paul C; Zhu, Jia L; Hennan, James; Balimane, Praveen; Yang, Zheng; Marino, Anthony M; Cornelius, Georgia; D'Arienzo, Celia J; Mathur, Arvind; Shen, Ding Ren; Cvijic, Mary Ellen; Salter-Cid, Luisa; Barrish, Joel C; Carter, Percy H; Dyckman, Alaric J

Variability in P-glycoprotein inhibitory potency (IC₅₀) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria

使用各种体外实验系统对 P-糖蛋白抑制效力 (IC₅₀) 的变化:对通用地高辛药物相互作用风险评估决策标准的影响

Joe Bentz, Michael P O'Connor, Dallas Bednarczyk, Joann Coleman, Caroline Lee, Johan Palm, Y Anne Pak, Elke S Perloff, Eric Reyner, Praveen Balimane, Marie Brännström, Xiaoyan Chu, Christoph Funk, Ailan Guo, Imad Hanna, Krisztina Herédi-Szabó, Kate Hillgren, Libin Li, Evelyn Hollnack-Pusch, Masoud J

Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions

应用受试者工作特征分析来完善对地高辛药物相互作用的潜在预测

Harma Ellens, Shibing Deng, Joann Coleman, Joe Bentz, Mitchell E Taub, Isabelle Ragueneau-Majlessi, Sophie P Chung, Krisztina Herédi-Szabó, Sibylle Neuhoff, Johan Palm, Praveen Balimane, Lei Zhang, Masoud Jamei, Imad Hanna, Michael O'Connor, Dallas Bednarczyk, Malin Forsgard, Xiaoyan Chu, Christoph

Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)

白细胞功能相关抗原-1 (LFA-1) 的小分子拮抗剂:结构-活性关系导致鉴定 6-((5S,9R)-9-(4-氰基苯基)-3-(3,5-二氯苯基)-1-甲基-2,4-二氧代-1,3,7-三氮杂螺[4.4]壬-7-基)烟酸 (BMS-688521)

Scott H Watterson, Zili Xiao, Dharmpal S Dodd, David R Tortolani, Wayne Vaccaro, Dominique Potin, Michele Launay, Dawn K Stetsko, Stacey Skala, Patric M Davis, Deborah Lee, Xiaoxia Yang, Kim W McIntyre, Praveen Balimane, Karishma Patel, Zheng Yang, Punit Marathe, Pathanjali Kadiyala, Andrew J Tebben

Current industrial practices of assessing permeability and P-glycoprotein interaction

目前工业界评估渗透性和P-糖蛋白相互作用的实践

Balimane, Praveen V; Han, Yong-Hae; Chong, Saeho