日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Assessment of systemic AAV-microdystrophin gene therapy in the GRMD model of Duchenne muscular dystrophy

在杜氏肌营养不良症GRMD模型中评估全身性AAV-微型肌营养不良蛋白基因治疗

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.abo1815
Birch, Sharla M; Lawlor, Michael W; Conlon, Thomas J; Guo, Lee-Jae; Crudele, Julie M; Hawkins, Eleanor C; Nghiem, Peter P; Ahn, Mihye; Meng, Hui; Beatka, Margaret J; Fickau, Brittany A; Prieto, Juan C; Styner, Martin A; Struharik, Michael J; Shanks, Courtney; Brown, Kristy J; Golebiowski, Diane; Bettis, Amanda K; Balog-Alvarez, Cynthia J; Clement, Nathalie; Coleman, Kirsten E; Corti, Manuela; Pan, Xiufang; Hauschka, Stephen D; Gonzalez, J Patrick; Morris, Carl A; Schneider, Joel S; Duan, Dongsheng; Chamberlain, Jeffrey S; Byrne, Barry J; Kornegay, Joe N
基因治疗
发表日期：2023
文献求助 收藏

Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MHCK7.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength

使用 rAAVrh74.MHCK7.GALGT2 对金毛猎犬肌营养不良症 (GRMD) 犬进行短期治疗可诱导肌肉糖基化和肌营养不良蛋白表达，但对肌肉强度没有显著影响

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0248721
Paul T Martin, Deborah A Zygmunt, Anna Ashbrook, Sonia Hamilton, Davin Packer, Sharla M Birch, Amanda K Bettis, Cynthia J Balog-Alvarez, Lee-Jae Guo, Peter P Nghiem, Joe N Kornegay
信号转导
发表日期：2021
文献求助 收藏

Correction: Challenges associated with homologous directed repair using CRISPR-Cas9 and TALEN to edit the DMD genetic mutation in canine Duchenne muscular dystrophy

更正：利用 CRISPR-Cas9 和 TALEN 进行同源定向修复以编辑犬杜氏肌营养不良症 (DMD) 基因突变所面临的挑战

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0241430
Mata López, Sara; Balog-Alvarez, Cynthia; Vitha, Stanislav; Bettis, Amanda K; Canessa, Emily H; Kornegay, Joe N; Nghiem, Peter P
DMD
发表日期：2020
文献求助 收藏

Oxidative damage to urinary proteins from the GRMD dog and mdx mouse as biomarkers of dystropathology in Duchenne muscular dystrophy.

GRMD 犬和 mdx 小鼠尿蛋白的氧化损伤作为杜氏肌营养不良症肌病病理学的生物标志物

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0240317
Terrill Jessica R, Al-Mshhdani Basma A, Duong Marisa N, Wingate Catherine D, Abbas Zahra, Baustista Angelo P, Bettis Amanda K, Balog-Alvarez Cynthia J, Kornegay Joe N, Nghiem Peter P, Grounds Miranda D, Arthur Peter G
免疫/内分泌
Mouse
发表日期：2020
文献求助 收藏

A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20

一种新型犬类杜氏肌营养不良症（DMD）模型：DMD基因第20外显子单核苷酸缺失

期刊:Skeletal Muscle
影响因子:4.4
doi:10.1186/s13395-018-0162-1
Mata López, Sara; Hammond, James J; Rigsby, Madison B; Balog-Alvarez, Cynthia J; Kornegay, Joe N; Nghiem, Peter P
DMD
发表日期：2018
文献求助 收藏

Expression profiling of disease progression in canine model of Duchenne muscular dystrophy

犬杜氏肌营养不良症模型中疾病进展的表达谱分析

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0194485
Candice Brinkmeyer-Langford, Candice Chu, Cynthia Balog-Alvarez, Xue Yu, James J Cai, Mary Nabity, Joe N Kornegay
发表日期：2018
文献求助 收藏

Glucose Metabolism as a Pre-clinical Biomarker for the Golden Retriever Model of Duchenne Muscular Dystrophy

葡萄糖代谢作为杜氏肌营养不良症金毛犬模型的临床前生物标志物

期刊:Molecular Imaging and Biology
影响因子:2.5
doi:10.1007/s11307-018-1174-2
Schneider, Sarah Morar; Sridhar, Vidya; Bettis, Amanda K; Heath-Barnett, Heather; Balog-Alvarez, Cynthia J; Guo, Lee-Jae; Johnson, Rachel; Jaques, Scott; Vitha, Stanislav; Glowcwski, Alan C; Kornegay, Joe N; Nghiem, Peter P
代谢
发表日期：2018
文献求助 收藏

Non-Targeted Metabolomics Analysis of Golden Retriever Muscular Dystrophy-Affected Muscles Reveals Alterations in Arginine and Proline Metabolism, and Elevations in Glutamic and Oleic Acid In Vivo

对患有金毛寻回犬肌营养不良症的肌肉进行非靶向代谢组学分析，揭示了精氨酸和脯氨酸代谢的改变以及体内谷氨酸和油酸水平的升高。

期刊:Metabolites
影响因子:3.7
doi:10.3390/metabo7030038
Abdullah, Muhammad; Kornegay, Joe N; Honcoop, Aubree; Parry, Traci L; Balog-Alvarez, Cynthia J; O'Neal, Sara K; Bain, James R; Muehlbauer, Michael J; Newgard, Christopher B; Patterson, Cam; Willis, Monte S
代谢
发表日期：2017
文献求助 收藏

Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy

全基因组测序揭示了一只患有肌营养不良症的狗的 DMD 外显子 42 中存在 7 个碱基对缺失

期刊:Mammalian Genome
影响因子:2.7
doi:10.1007/s00335-016-9675-2
Peter P Nghiem, Luca Bello, Cindy Balog-Alvarez, Sara Mata López, Amanda Bettis, Heather Barnett, Briana Hernandez, Scott J Schatzberg, Richard J Piercy, Joe N Kornegay
DMD
发表日期：2017
文献求助 收藏

Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures

缺乏肌营养不良蛋白且肌生长抑制素减少的狗，其肌肉生长不均衡，关节挛缩更严重

期刊:Skeletal Muscle
影响因子:5.3
doi:10.1186/s13395-016-0085-7
Joe N Kornegay, Daniel J Bogan, Janet R Bogan, Jennifer L Dow, Jiahui Wang, Zheng Fan, Naili Liu, Leigh C Warsing, Robert W Grange, Mihye Ahn, Cynthia J Balog-Alvarez, Steven W Cotten, Monte S Willis, Candice Brinkmeyer-Langford, Hongtu Zhu, Joe Palandra, Carl A Morris, Martin A Styner, Kathryn R Wa
信号转导
发表日期：2016
文献求助 收藏