日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation

重氮代谢物的化学捕获揭示了生物合成腙氧化反应

Pfeifer, Katarina; Van Cura, Devon; Wu, Kelvin J Y; Balskus, Emily P

Flavoaffinins, Elusive Cellulose-Binding Natural Products from an Anaerobic Bacterium

黄素亲和素,一种来自厌氧细菌的难以捉摸的纤维素结合天然产物

Kountz, Duncan J; Yu, Ruocheng; Lee, Jessie H; Maloney, Katherine N; Balskus, Emily P

Phenotypic high-throughput screening identifies modulators of gut microbial choline metabolism

表型高通量筛选鉴定肠道微生物胆碱代谢的调节因子

Woo, Amelia Y M; Sandoval-Espinola, Walter J; Bollenbach, Maud; Wong, Alison; Sakanaka-Yokoyama, Mariko; Zhang, Qijun; Nieto, Vincent; Rey, Federico E; Balskus, Emily P

A previously unappreciated class of metal-dependent bile salt hydrolases from the human gut microbiome

人类肠道微生物组中一类此前未被重视的金属依赖性胆汁盐水解酶

Cui, Zheng; Meng, Christopher J; Irwin, Stephania M; Augustijn, Hannah E; Papageorgiou, Panagiotis Panagopoulos; Nguyen, Anh T P; Yu, Ruocheng; Aguilar Ramos, Miguel A; Kulik, Heather J; Balskus, Emily P

The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin

肠道细菌基因毒素大肠杆菌素对DNA交联的特异性和结构

Carlson, Erik S; Haslecker, Raphael; Lecchi, Chiara; Aguilar Ramos, Miguel A; Vennelakanti, Vyshnavi; Honaker, Linda; Stornetta, Alessia; Millán, Estela S; Johnson, Bruce A; Kulik, Heather J; Balbo, Silvia; Villalta, Peter W; D'Souza, Victoria M; Balskus, Emily P

The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links

范可尼贫血通路修复大肠杆菌素诱导的DNA链间交联

Altshuller, Maria; He, Xu; MacKrell, Elliot J; Wernke, Kevin M; Airan, Yougant; Wong, Joel W H; Sellés-Baiget, Selene; Wang, Ting-Yu; Chou, Tsui-Fen; Duxin, Julien P; Balskus, Emily P; Herzon, Seth B; Semlow, Daniel R

Enantiocomplementary Gut Bacterial Enzymes Metabolize Dietary Polyphenols

对映互补的肠道细菌酶代谢膳食多酚

Dong, Xueyang; Bae, Minwoo; Le, Chi; Aguilar Ramos, Miguel A; Balskus, Emily P

Characterizing and engineering post-translational modifications with high-throughput cell-free expression

利用高通量无细胞表达技术对翻译后修饰进行表征和工程改造

Derek A Wong # ,Zachary M Shaver # ,Maria D Cabezas ,Martin Daniel-Ivad ,Katherine F Warfel ,Deepali V Prasanna ,Sarah E Sobol ,Regina Fernandez ,Fernando Tobias ,Szymon K Filip ,Sophia W Hulbert ,Peter Faull ,Robert Nicol ,Matthew P DeLisa ,Emily P Balskus ,Ashty S Karim ,Michael C Jewett

Distinct classes of gut bacterial molybdenum-dependent enzymes produce urolithins

肠道细菌中不同类型的钼依赖性酶可产生尿石素。

Bae, Minwoo; Dong, Xueyang; Avila-Pacheco, Julian; Nguyen, Quyen D; Inyama, Fechi; Hill-Maini, Vayu; Clish, Clary B; Balskus, Emily P

A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury

一种小分子肠道细菌尿素酶抑制剂可保护宿主免受肝损伤

Richards-Corke, Khyle C; Jiang, Yindi; Yeliseyev, Vladimir; Zhang, Yancong; Franzosa, Eric A; Wang, Zhipeng A; Yapa Abeywardana, Maheeshi; Cole, Phillip A; Huttenhower, Curtis; Bry, Lynn; Balskus, Emily P