A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance
冠状病毒nsp13解旋酶的突变会损害酶活性并赋予其对瑞德西韦的部分耐药性。
期刊:mBio
影响因子:4.7
doi:10.1128/mbio.01060-23
Grimes, Samantha L; Choi, Young J; Banerjee, Anoosha; Small, Gabriel; Anderson-Daniels, Jordan; Gribble, Jennifer; Pruijssers, Andrea J; Agostini, Maria L; Abu-Shmais, Alexandra; Lu, Xiaotao; Darst, Seth A; Campbell, Elizabeth; Denison, Mark R