Discovery of (E)-1,3-Diphenyl-2-Propen-1-One Derivatives as Potent and Orally Active NLRP3 Inflammasome Inhibitors for Colitis
发现 (E)-1,3-二苯基-2-丙烯-1-酮衍生物作为强效口服活性 NLRP3 炎症小体抑制剂用于治疗结肠炎
期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30163340
Chen, Liuzeng; Zheng, Xiaoyu; Li, Jiahui; Zhou, Bin; Tao, Min; Yang, Yuetian; Wang, Yi; Zhan, Hao; Zhang, Guoping; Shi, Jingbo; Zhang, Xingxing; Ruan, Banfeng
炎症
肠炎
炎症/感染
LRP3
NLRP3
结肠炎
炎性小体
免疫/内分泌
