日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In silico biological discovery with large perturbation models

利用大扰动模型进行计算机生物学发现

Miladinovic, Djordje; Höppe, Tobias; Chevalley, Mathieu; Georgiou, Andreas; Stuart, Lachlan; Mehrjou, Arash; Bantscheff, Marcus; Schölkopf, Bernhard; Schwab, Patrick

A Probe-Based Target Engagement Assay for Kinases in Live Cells.

基于探针的活细胞激酶靶标结合分析

Glocker Ursula M, Braun Florian, Eberl H Christian, Bantscheff Marcus

Network integration of thermal proteome profiling with multi-omics data decodes PARP inhibition

热蛋白质组分析与多组学数据的网络整合可解码 PARP 抑制

Mira L Burtscher, Stephan Gade, Martin Garrido-Rodriguez, Anna Rutkowska, Thilo Werner, H Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Fälth-Savitski, Julio Saez-Rodriguez

The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages

抗癌人类 mTOR 抑制剂 sapanisertib 可有效抑制多种疟原虫激酶和生命周期阶段

Lauren B Arendse, James M Murithi, Tarrick Qahash, Charisse Flerida A Pasaje, Luiz C Godoy, Sumanta Dey, Liezl Gibhard, Sonja Ghidelli-Disse, Gerard Drewes, Marcus Bantscheff, Maria J Lafuente-Monasterio, Stephen Fienberg, Lynn Wambua, Samuel Gachuhi, Dina Coertzen, Mariëtte van der Watt, Janette Re

Systematic discovery of biomolecular condensate-specific protein phosphorylation

系统发现生物分子凝聚物特异性蛋白质磷酸化

Sindhuja Sridharan, Alberto Hernandez-Armendariz, Nils Kurzawa, Clement M Potel, Danish Memon, Pedro Beltrao, Marcus Bantscheff, Wolfgang Huber, Sara Cuylen-Haering, Mikhail M Savitski

Interval-Based Secretomics Unravels Acute-Phase Response in Hepatocyte Model Systems

基于间隔的秘密组学揭示肝细胞模型系统中的急性期反应

Sascha Knecht, H Christian Eberl, Marcus Bantscheff

1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in Mycobacterium tuberculosis

1,3-二芳基吡唑酰基磺酰胺靶向结核分枝杆菌中的 HadAB/BC 复合物

Vinayak Singh, Anna E Grzegorzewicz, Stephen Fienberg, Rudolf Müller, Lutete Peguy Khonde, Olalla Sanz, Salvatore Alfonso, Beatriz Urones, Gerard Drewes, Marcus Bantscheff, Sonja Ghidelli-Disse, Thomas R Ioerger, Bhanupriya Angala, Jiuyu Liu, Richard E Lee, James C Sacchettini, Inna V Krieger, Mary

Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane

细胞表面热蛋白质组分析追踪质膜上的扰动和药物靶标

Mathias Kalxdorf, Ina Günthner, Isabelle Becher, Nils Kurzawa, Sascha Knecht, Mikhail M Savitski, H Christian Eberl, Marcus Bantscheff

SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

SARS-CoV-2 驱动 JAK1/2 依赖性局部补体过度激活

Bingyu Yan # ,Tilo Freiwald # ,Daniel Chauss # ,Luopin Wang # ,Erin West # ,Carmen Mirabelli ,Charles J Zhang ,Eva-Maria Nichols ,Nazish Malik ,Richard Gregory ,Marcus Bantscheff ,Sonja Ghidelli-Disse ,Martin Kolev ,Tristan Frum ,Jason R Spence ,Jonathan Z Sexton ,Konstantinos D Alysandratos ,Darrell N Kotton ,Stefania Pittaluga ,Jack Bibby ,Nathalie Niyonzima ,Matthew R Olson ,Shahram Kordasti ,Didier Portilla ,Christiane E Wobus ,Arian Laurence ,Michail S Lionakis ,Claudia Kemper # ,Behdad Afzali # ,Majid Kazemian #

Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

作者更正:一种从剂量范围热蛋白质组谱中检测配体结合蛋白的计算方法

Kurzawa, Nils; Becher, Isabelle; Sridharan, Sindhuja; Franken, Holger; Mateus, André; Anders, Simon; Bantscheff, Marcus; Huber, Wolfgang; Savitski, Mikhail M