日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In silico biological discovery with large perturbation models

利用大扰动模型进行计算机生物学发现

Miladinovic, Djordje; Höppe, Tobias; Chevalley, Mathieu; Georgiou, Andreas; Stuart, Lachlan; Mehrjou, Arash; Bantscheff, Marcus; Schölkopf, Bernhard; Schwab, Patrick

A Probe-Based Target Engagement Assay for Kinases in Live Cells.

基于探针的活细胞激酶靶标结合分析

Glocker Ursula M, Braun Florian, Eberl H Christian, Bantscheff Marcus

Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

作者更正:一种从剂量范围热蛋白质组谱中检测配体结合蛋白的计算方法

Kurzawa, Nils; Becher, Isabelle; Sridharan, Sindhuja; Franken, Holger; Mateus, André; Anders, Simon; Bantscheff, Marcus; Huber, Wolfgang; Savitski, Mikhail M

A Bayesian semi-parametric model for thermal proteome profiling

用于热蛋白质组分析的贝叶斯半参数模型

Fang, Siqi; Kirk, Paul D W; Bantscheff, Marcus; Lilley, Kathryn S; Crook, Oliver M

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

一种利用剂量范围热蛋白质组谱检测配体结合蛋白的计算方法

Kurzawa, Nils; Becher, Isabelle; Sridharan, Sindhuja; Franken, Holger; Mateus, André; Anders, Simon; Bantscheff, Marcus; Huber, Wolfgang; Savitski, Mikhail M

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

蛋白质组范围的溶解度和热稳定性分析揭示了ATP的独特调控作用

Sridharan, Sindhuja; Kurzawa, Nils; Werner, Thilo; Günthner, Ina; Helm, Dominic; Huber, Wolfgang; Bantscheff, Marcus; Savitski, Mikhail M

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

发现高选择性和强效的TBK1抑制剂GSK8612

Thomson, Douglas W; Poeckel, Daniel; Zinn, Nico; Rau, Christina; Strohmer, Katrin; Wagner, Anne J; Graves, Alan P; Perrin, Jessica; Bantscheff, Marcus; Duempelfeld, Birgit; Kasparcova, Viera; Ramanjulu, Joshi M; Pesiridis, G Scott; Muelbaier, Marcel; Bergamini, Giovanna

Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo

基于Tau蛋白相互作用组图谱的鉴定表明,Otub1是Tau蛋白去泛素化酶,参与体外和体内病理性Tau蛋白的积累。

Wang, Peng; Joberty, Gerard; Buist, Arjan; Vanoosthuyse, Alexandre; Stancu, Ilie-Cosmin; Vasconcelos, Bruno; Pierrot, Nathalie; Faelth-Savitski, Maria; Kienlen-Campard, Pascal; Octave, Jean-Noël; Bantscheff, Marcus; Drewes, Gerard; Moechars, Diederik; Dewachter, Ilse

Activation of the Amino Acid Response Pathway Blunts the Effects of Cardiac Stress

氨基酸反应通路激活可减轻心脏应激的影响

Qin, Pu; Arabacilar, Pelin; Bernard, Roberta E; Bao, Weike; Olzinski, Alan R; Guo, Yuanjun; Lal, Hind; Eisennagel, Stephen H; Platchek, Michael C; Xie, Wensheng; Del Rosario, Julius; Nayal, Mohamad; Lu, Quinn; Roethke, Theresa; Schnackenberg, Christine G; Wright, Fe; Quaile, Michael P; Halsey, Wendy S; Hughes, Ashley M; Sathe, Ganesh M; Livi, George P; Kirkpatrick, Robert B; Qu, Xiaoyan A; Rajpal, Deepak K; Faelth Savitski, Maria; Bantscheff, Marcus; Joberty, Gerard; Bergamini, Giovanna; Force, Thomas L; Gatto, Gregory J Jr; Hu, Erding; Willette, Robert N

Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B

发现并表征了 GSK2801,一种选择性针对溴结构域 BAZ2A 和 BAZ2B 的化学探针

Chen, Peiling; Chaikuad, Apirat; Bamborough, Paul; Bantscheff, Marcus; Bountra, Chas; Chung, Chun-Wa; Fedorov, Oleg; Grandi, Paola; Jung, David; Lesniak, Robert; Lindon, Matthew; Müller, Susanne; Philpott, Martin; Prinjha, Rab; Rogers, Catherine; Selenski, Carolyn; Tallant, Cynthia; Werner, Thilo; Willson, Timothy M; Knapp, Stefan; Drewry, David H