日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer

H3K9 甲基化导致前列腺癌对雄激素受体拮抗剂治疗产生耐药性

Mehdi Baratchian, Ritika Tiwari, Sirvan Khalighi, Ankur Chakravarthy, Wei Yuan, Michael Berk, Jianneng Li, Amy Guerinot, Johann de Bono, Vladimir Makarov, Timothy A Chan, Robert H Silverman, George R Stark, Vinay Varadan, Daniel D De Carvalho, Abhishek A Chakraborty, Nima Sharifi

Hexose-6-phosphate dehydrogenase blockade reverses prostate cancer drug resistance in xenograft models by glucocorticoid inactivation

己糖-6-磷酸脱氢酶阻断可通过糖皮质激素失活逆转异种移植模型中的前列腺癌耐药性

Jianneng Li, Michael Berk, Mohammad Alyamani, Navin Sabharwal, Christopher Goins, Joseph Alvarado, Mehdi Baratchian, Ziqi Zhu, Shaun Stauffer, Eric A Klein, Nima Sharifi

Androgen regulation of pulmonary AR, TMPRSS2 and ACE2 with implications for sex-discordant COVID-19 outcomes

雄激素对肺 AR、TMPRSS2 和 ACE2 的调节与性别不一致的 COVID-19 结果有关

Mehdi Baratchian, Jeffrey M McManus, Mike P Berk, Fumihiko Nakamura, Sanjay Mukhopadhyay, Weiling Xu, Serpil Erzurum, Judy Drazba, John Peterson, Eric A Klein, Benjamin Gaston, Nima Sharifi

Sex, androgens and regulation of pulmonary AR, TMPRSS2 and ACE2

性别、雄激素和肺 AR、TMPRSS2 和 ACE2 的调节

Mehdi Baratchian, Jeffrey M McManus, Mike Berk, Fumihiko Nakamura, Sanjay Mukhopadhyay, Weiling Xu, Serpil Erzurum, Judy Drazba, John Peterson, Eric A Klein, Ben Gaston, Nima Sharifi

IKKγ-Mimetic Peptides Block the Resistance to Apoptosis Associated with Kaposi's Sarcoma-Associated Herpesvirus Infection

IKKγ-模拟肽阻断与卡波西肉瘤相关疱疹病毒感染相关的细胞凋亡抵抗

Louise C Briggs, A W Edith Chan, Christopher A Davis, Nicholas Whitelock, Hajira A Hotiana, Mehdi Baratchian, Claire Bagnéris, David L Selwood, Mary K Collins, Tracey E Barrett

Distinct Activation Mechanisms of NF-κB Regulator Inhibitor of NF-κB Kinase (IKK) by Isoforms of the Cell Death Regulator Cellular FLICE-like Inhibitory Protein (cFLIP)

细胞死亡调节剂细胞 FLICE 样抑制蛋白 (cFLIP) 异构体对 NF-κB 激酶 (IKK) NF-κB 调节剂抑制剂的不同激活机制

Mehdi Baratchian, Christopher A Davis, Akira Shimizu, David Escors, Claire Bagnéris, Tracey Barrett, Mary K Collins

Association of C1q/TNF-Related Protein-3 (CTRP3) and CTRP13 Serum Levels with Coronary Artery Disease in Subjects with and without Type 2 Diabetes Mellitus

患有和不患有 2 型糖尿病的受试者中 C1q/TNF 相关蛋白 3 (CTRP3) 和 CTRP13 血清水平与冠状动脉疾病的关联

Reza Fadaei, Nariman Moradi, Mehdi Baratchian, Hassan Aghajani, Mojtaba Malek, Ali Akbar Fazaeli, Soudabeh Fallah

Probing the solution structure of IκB kinase (IKK) subunit γ and its interaction with Kaposi sarcoma-associated herpes virus Flice-interacting protein and IKK subunit β by EPR spectroscopy

利用电子顺磁共振波谱法探测IκB激酶(IKK)γ亚基的溶液结构及其与卡波西肉瘤相关疱疹病毒Flice相互作用蛋白和IKK β亚基的相互作用

Bagnéris, Claire; Rogala, Kacper B; Baratchian, Mehdi; Zamfir, Vlad; Kunze, Micha B A; Dagless, Selina; Pirker, Katharina F; Collins, Mary K; Hall, Benjamin A; Barrett, Tracey E; Kay, Christopher W M

Kaposi's sarcoma-associated herpesvirus vFLIP and human T cell lymphotropic virus type 1 Tax oncogenic proteins activate IkappaB kinase subunit gamma by different mechanisms independent of the physiological cytokine-induced pathways

卡波西肉瘤相关疱疹病毒vFLIP和人类T细胞淋巴瘤病毒1型Tax致癌蛋白通过不同的机制激活IκB激酶亚基γ,这些机制独立于生理细胞因子诱导的通路。

Shimizu, Akira; Baratchian, Mehdi; Takeuchi, Yasu; Escors, David; Macdonald, Douglas; Barrett, Tracey; Bagneris, Claire; Collins, Mary; Noursadeghi, Mahdad