日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy

西伯利林是一种新型的坏死性凋亡和铁死亡双重抑制剂,它能抑制RIPK1激酶活性和(磷脂)脂质过氧化,因此具有潜在的治疗价值。

Delehouzé, Claire; Mallais, Melodie; Comte, Arnaud; Lucas, Romain; Baratte, Blandine; Bélal, Sophie; Autret, Axelle; Py, Nathalie; Steinschneider, Rémy; Adoux, Lucie; Saintpierre, Benjamin; Letourneur, Franck; Robert, Thomas; Cougoule, Céline; Bomfim, Caio; Planès, Rémi; Péricat, David; Bulinski, Jeannette Chloë; Dimanche-Boitrel, Marie-Thérèse; Goekjian, Peter; Meunier, Etienne; Rousselot, Morgane; Pratt, Derek A; Bach, Stéphane

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.

在设计靶向酪蛋白激酶 1 的有前景的咪唑并[1,2-a]吡嗪衍生物以进行抗利什曼原虫治疗时,以药效团为指导对先导化合物 CTN1122 进行优化

Tisseur Lhana, Logé Cédric, Cojean Sandrine, Gassama Khadidiatou, Karcher Lilian, Pagniez Fabrice, Cavé Christian, Bernadat Guillaume, Loiseau Philippe M, Bach Stéphane, Thiéfaine Jérôme, Bonnet Justine, Picot Carine, Tomasoni Christophe, Leclercq Olivier, Baratte Blandine, Robert Thomas, Le Pape Patrice, Rachidi Najma, Bazin Marc-Antoine, Marchand Pascal

Research towards selective inhibition of the CLK3 kinase

针对CLK3激酶选择性抑制的研究

Singh, Vinay Kumar; Justaud, Frédéric; Brahmaiah, Dabbugoddu; Kumar, Nangunoori Sampath; Baratte, Blandine; Robert, Thomas; Bach, Stéphane; Reddy, Chada Raji; Levoin, Nicolas; Grée, René L

New Fusarochromanone Derivatives from the Marine Fungus Fusarium equiseti UBOCC-A-117302.

来自海洋真菌 Fusarium equiseti UBOCC-A-117302 的新型 Fusarochromanone 衍生物

Pham Giang Nam, Josselin Béatrice, Cousseau Arnaud, Baratte Blandine, Dayras Marie, Le Meur Christophe, Debaets Stella, Weill Amélie, Robert Thomas, Burgaud Gaëtan, Probert Ian, Abdoul-Latif Fatouma Mohamed, Boyer Laurent, Bach Stéphane, Mehiri Mohamed

Novel Thiazole-Fused [4,5-g] or [5,4-g]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation.

新型噻唑稠合[4,5-g]或[5,4-g]喹唑啉-8-酮及其喹唑啉类似物:合成和生物学评价

Broudic Nathan, Pacheco-Benichou Alexandra, Corbière Cécile, Baratte Blandine, Robert Thomas, Bach Stéphane, Solhi Hélène, Le Guével Rémy, Fruit Corinne, Besson Thierry

Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration

依那维林和罂粟碱靶向细胞周期蛋白依赖性激酶5,抑制肺癌细胞增殖和迁移

Laure, Arthur; Royet, Chloé; Bihel, Frederic; Baratte, Blandine; Bach, Stéphane; Peyressatre, Marion; Morris, May C

No Long-Term Mucosal Lesions in the Esophagus but More Gastric Mucosal Lesions after Sleeve Gastrectomy in Obese Rats

肥胖大鼠袖状胃切除术后食管未见长期黏膜损伤,但胃黏膜损伤较多

Coupaye, Muriel; Ribeiro-Parenti, Lara; Baratte, Clément; Hourseau, Muriel; Willemetz, Alexandra; Duboc, Henri; Ledoux, Séverine; Bado, André; Couvelard, Anne; Le Gall, Maude

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

针对 CLK 激酶的强效选择性抑制剂 DB18 的构效关系研究

Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi, Rémy Le Guevel, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach, Surender Singh Jadav, Chada Raji Reddy, Paul Mosset, Nicolas Gouault, Nicolas Levoin, René Grée

Good tolerance of hyaluronic acid injections during the period of the COVID-19 pandemic: observing a cohort of 1093 patients in a prospective, observational real-life study

COVID-19 大流行期间玻尿酸注射耐受性良好:一项前瞻性、观察性真实世界研究对 1093 名患者进行的观察

Naouri, M; Dahan, S; Le Pillouer Prost, A; Coutant-Foulc, P; Raimbault, C; Cucurella, F; Beille, L; Creusot, M; Baspeyras, M; Darchy, M; Khallouf, R; Cartier, H; Baratte, I; Dubois, M; Cogrel, O; Laubach, H

Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

桦木醇是金合欢树皮中一种新鉴定的化合物,是一种多靶点蛋白激酶抑制剂

Augustine A Ahmadu, Claire Delehouzé, Anas Haruna, Lukman Mustapha, Bilqis A Lawal, Aniefiok Udobre, Blandine Baratte, Camilla Triscornia, Axelle Autret, Thomas Robert, Jeannette Chloë Bulinski, Morgane Rousselot, Mélanie Simoes Eugénio, Marie-Thérèse Dimanche-Boitrel, Jacobus P Petzer, Lesetja J Le