日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sibiriline, a novel dual inhibitor of necroptosis and ferroptosis, prevents RIPK1 kinase activity and (phospho)lipid peroxidation as a potential therapeutic strategy

西伯利林是一种新型的坏死性凋亡和铁死亡双重抑制剂,它能抑制RIPK1激酶活性和(磷脂)脂质过氧化,因此具有潜在的治疗价值。

Delehouzé, Claire; Mallais, Melodie; Comte, Arnaud; Lucas, Romain; Baratte, Blandine; Bélal, Sophie; Autret, Axelle; Py, Nathalie; Steinschneider, Rémy; Adoux, Lucie; Saintpierre, Benjamin; Letourneur, Franck; Robert, Thomas; Cougoule, Céline; Bomfim, Caio; Planès, Rémi; Péricat, David; Bulinski, Jeannette Chloë; Dimanche-Boitrel, Marie-Thérèse; Goekjian, Peter; Meunier, Etienne; Rousselot, Morgane; Pratt, Derek A; Bach, Stéphane

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2-a]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy.

在设计靶向酪蛋白激酶 1 的有前景的咪唑并[1,2-a]吡嗪衍生物以进行抗利什曼原虫治疗时,以药效团为指导对先导化合物 CTN1122 进行优化

Tisseur Lhana, Logé Cédric, Cojean Sandrine, Gassama Khadidiatou, Karcher Lilian, Pagniez Fabrice, Cavé Christian, Bernadat Guillaume, Loiseau Philippe M, Bach Stéphane, Thiéfaine Jérôme, Bonnet Justine, Picot Carine, Tomasoni Christophe, Leclercq Olivier, Baratte Blandine, Robert Thomas, Le Pape Patrice, Rachidi Najma, Bazin Marc-Antoine, Marchand Pascal

Research towards selective inhibition of the CLK3 kinase

针对CLK3激酶选择性抑制的研究

Singh, Vinay Kumar; Justaud, Frédéric; Brahmaiah, Dabbugoddu; Kumar, Nangunoori Sampath; Baratte, Blandine; Robert, Thomas; Bach, Stéphane; Reddy, Chada Raji; Levoin, Nicolas; Grée, René L

New Fusarochromanone Derivatives from the Marine Fungus Fusarium equiseti UBOCC-A-117302.

来自海洋真菌 Fusarium equiseti UBOCC-A-117302 的新型 Fusarochromanone 衍生物

Pham Giang Nam, Josselin Béatrice, Cousseau Arnaud, Baratte Blandine, Dayras Marie, Le Meur Christophe, Debaets Stella, Weill Amélie, Robert Thomas, Burgaud Gaëtan, Probert Ian, Abdoul-Latif Fatouma Mohamed, Boyer Laurent, Bach Stéphane, Mehiri Mohamed

Novel Thiazole-Fused [4,5-g] or [5,4-g]Quinazolin-8-ones and Their Quinazoline Analogues: Synthesis and Biological Evaluation.

新型噻唑稠合[4,5-g]或[5,4-g]喹唑啉-8-酮及其喹唑啉类似物:合成和生物学评价

Broudic Nathan, Pacheco-Benichou Alexandra, Corbière Cécile, Baratte Blandine, Robert Thomas, Bach Stéphane, Solhi Hélène, Le Guével Rémy, Fruit Corinne, Besson Thierry

Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration

依那维林和罂粟碱靶向细胞周期蛋白依赖性激酶5,抑制肺癌细胞增殖和迁移

Laure, Arthur; Royet, Chloé; Bihel, Frederic; Baratte, Blandine; Bach, Stéphane; Peyressatre, Marion; Morris, May C

Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation

设计新型二取代咪唑并[1,2-b]哒嗪衍生物作为选择性Haspin抑制剂。合成、结合模式及抗癌生物学评价

Elie, Jonathan; Feizbakhsh, Omid; Desban, Nathalie; Josselin, Béatrice; Baratte, Blandine; Bescond, Amandine; Duez, Julien; Fant, Xavier; Bach, Stéphane; Marie, Dominique; Place, Matthieu; Ben Salah, Sami; Chartier, Agnes; Berteina-Raboin, Sabine; Chaikuad, Apirat; Knapp, Stefan; Carles, Fabrice; Bonnet, Pascal; Buron, Frédéric; Routier, Sylvain; Ruchaud, Sandrine

Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents

芳基半卡巴腙衍生物作为潜在抗癌药物的生物学评价

Nascimento da Cruz, Anne Cecília; Brondani, Dalci José; I Talo de Santana, Temístocles; Oliveira da Silva, Lucas; da Oliveira Borba, Elizabeth Fernanda; de Faria, Antônio Rodolfo; Ferreira Cavalcanti de Albuquerque, Julianna; Piessard, Sylvie; Matos Ximenes, Rafael; Baratte, Blandine; Bach, Stéphane; Ruchaud, Sandrine; Bezerra Mendonça Junior, Francisco Jaime; Bazin, Marc-Antoine; Montenegro Rabello, Marcelo; Hernandes, Marcelo Zaldini; Marchand, Pascal; Gonçalves da Silva, Teresinha

Correction to: Phenytoin inhibits necroptosis

更正:苯妥英钠抑制坏死性凋亡

von Mässenhausen, Anne; Tonnus, Wulf; Himmerkus, Nina; Parmentier, Simon; Saleh, Danish; Rodriguez, Diego; Ousingsawat, Jiraporn; Ang, Rosalind L; Weinberg, Joel M; Sanz, Ana B; Ortiz, Alberto; Zierleyn, Adrian; Becker, Jan Ulrich; Baratte, Blandine; Desban, Nathalie; Bach, Stéphane; Schiessl, Ina Maria; Nogusa, Shoko; Balachandran, Siddharth; Anders, Hans Joachim; Ting, Adrian T; Bleich, Markus; Degterev, Alexei; Kunzelmann, Karl; Bornstein, Stefan R; Green, Douglas R; Hugo, Christian; Linkermann, Andreas

Bioactive Metabolites from the Deep Subseafloor Fungus Oidiodendron griseum UBOCC-A-114129

来自深海海底真菌灰褐丝绒菌(Oidiodendron griseum UBOCC-A-114129)的生物活性代谢物

Navarri, Marion; Jégou, Camille; Bondon, Arnaud; Pottier, Sandrine; Bach, Stéphane; Baratte, Blandine; Ruchaud, Sandrine; Barbier, Georges; Burgaud, Gaëtan; Fleury, Yannick