日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens

一种独特的抑制剂构象选择性地靶向革兰氏阳性优先病原体的DNA聚合酶PolC

Urem, Mia; Friggen, Annemieke H; Musch, Nina; Silverman, Michael H; Swain, Christopher J; Barbachyn, Michael R; Mortin, Lawrence I; Yu, Xiang; DeLuccia, Robert J; Lamers, Meindert H; Smits, Wiep Klaas

Identification of a 1,2,4-Oxadiazole with Potent and Specific Activity against Clostridioides difficile, the Causative Bacterium of C. difficile Infection, an Urgent Public Health Threat

鉴定出一种对艰难梭菌(引起艰难梭菌感染的病原菌,一种紧迫的公共卫生威胁)具有强效和特异性活性的1,2,4-恶二唑

Barbachyn, Michael R

Bacterial efflux pump modulators prevent bacterial growth in macrophages and under broth conditions that mimic the host environment

细菌外排泵调节剂可防止细菌在巨噬细胞中以及在模拟宿主环境的肉汤条件下生长

Samual C Allgood #, Chih-Chia Su #, Amy L Crooks, Christian T Meyer, Bojun Zhou, Meredith D Betterton, Michael R Barbachyn, Edward W Yu, Corrella S Detweiler

Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment

细菌外排泵调节剂可防止巨噬细胞中以及模拟宿主环境的肉汤条件下的细菌生长

Samual C Allgood, Chih-Chia Su, Amy L Crooks, Christian T Meyer, Bojun Zhou, Meredith D Betterton, Michael R Barbachyn, Edward W Yu, Corrella S Detweiler